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    Influenza pandemics occur with some frequency, as indicated by the recent outbreak of swine flu (influenza A (H1N1)). Learn more about influenza, previous 'flu pandemics, preventative measures against 'flu and how the spread of disease can be modelled and possibly predicted with these selected Nature Reviews MicrobiologyandNature Reviews Geneticsarticles.

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    At the point when theory is about to be translated into practice in genomic medicine, this collection of Perspective articles describes human genome variation studies taking place in Mexico, India, Thailand, and South Africa. This Supplement discusses the challenges and opportunities facing these and other countries in the developing world as they begin to harness genomics for the benefit of their populations.

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    MicroRNAs (miRNAs) — an abundant class of small non–protein–coding regulators of gene expression — play an important role in tumorigenesis and, depending on their targets, can function as tumour suppressors or oncogenes. Crucially, miRNA–expression profiling of human tumours has identified signatures associated with diagnosis, staging, progression, prognosis and response to treatment.

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    Nature Reviews presents a Collection on microRNAs, which includes Reviews from Nature Reviews Genetics,Nature Reviews CancerandNature Reviews Molecular Cell Biology. The articles have been specially selected to provide an introduction to diverse aspects of microRNA biology, including their biogenesis, function in normal development and cancer, and evolutionary implications of their impact on gene regulation.