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Administration of the clinically approved iron oxide nanoparticle drug ferumoxytol in vitro results in an anti-leukaemia effect and in vivo extended overall survival in part due to the low expression of the iron export protein ferroportin.
Overcrowded alkene-based motors are made part of the crystalline structure of a metal–organic framework. It is shown that they retain the same rotatory speed and unidirectionality as in solution.
A vertical, electrolyte-gated organic transistor shows high on-state current densities, large on/off ratio and the potential for use in artificial neural networks.
Gate-tuning of a Fermi reservoir enables the deterministic loading of single electrons or holes into a localized quantum dot in a WSe2 monolayer and the observation of hybrid excitons originating from strong, spin-conserving tunnelling between the dot and the reservoir.
Under the application of a magnetic field, the 2D electron gas in a gated MoS2 monolayer becomes spin-polarized, the Coulomb interaction probably being key to the symmetry breaking.
Instead of using capacitively coupled charge sensors, which imply additional complexity in the device architecture, radiofrequency reflectometry on the gate defining the quantum dot can read out the spin state of a double quantum dot in a single shot.
A scanning single-electron transistor-based method enables simultaneous visualization of voltage and current density of flowing electrons in two-dimensional systems with high sensitivity and minimal invasiveness
While neutral-charge quantum dots in optically active WSe2 do not show spin-valley initialization, localized holes possess a net spin and their spin-valley state can be selected with the helicity of the laser excitation.
Miniaturized gold nanorods are reliable NIR-II photoacoustic agents, showing higher photothermal stability, enhanced photoacoustic signal and more efficient agent-to-tumour delivery compared with their larger counterparts.
Lanthanide-doped nanoparticles could be used as labels for the imaging of biomolecules, potentially leading to a multicolour modality in electron microscopy.
Semipermeable proteinosome membranes allow complex DNA message communication through compartmentalization and protect the DNA circuits from degradation in a biological environment.
High aspect ratio nanomaterials enable efficient delivery of DNA into mature plant cells in a species-independent and non-integrating manner for plant genetic engineering applications.
Sub-micrometre spin waves are excited in anisotropic spin textures and they can propagate as 2D plane waves over several micrometres and as 1D waves along curved domain walls.
Inhibiting POLR2A expression upon siRNA delivery represents a promising therapeutic strategy for triple negative breast cancers characterized by p53 inactivation.
Chitosan-functionalized single-walled carbon nanotubes enable selective gene delivery to the chloroplasts of mature living plants without external mechanical aid.
A combination of light-emitting semiconductors and photochromic molecules enables the fabrication of optically switchable organic light-emitting transistors with tunable current and luminance.