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The antimicrobial agent epifadin, which is produced by the nasal commensal Staphylococcus epidermidis, has— despite its short half-life — broad-spectrum activity, including against Staphylococcus aureus.
Bacteroides fragilis employs two different mechanisms, secreted microbe- and host-targeting toxins, that facilitate successful colonization of the mammalian gastrointestinal tract.