News & Comment

Creativity, passion, inclusion and a targeted way to study circular RNAs.

High-density microelectrode arrays with dual-mode capabilities can ‘image’ electrical activity in neuronal cultures or slice preparations.

RNA timestamps are molecular recorders that enable one to infer the age of an RNA molecule and record transcriptional activity in a temporal manner.

Technological advances push the limits of single-particle cryo-EM to achieve atomic resolution.

A new method should be thoroughly tested, applied, described — and peer-reviewed — before biological discoveries generated using the method are published.

A soccer striker and his ion channel rescue tools.

CRISPR, now a Nobel-Prize-winning technology, comes in many flavors. And so do gRNAs.

X-ray holographic nano-tomography is a promising complement to electron microscopy for connectomics studies.

This month, we celebrate the beauty and power of microscopy images.

van der Mers (vdMs), a unit of protein structure, facilitate de novo design of proteins that bind small molecules.

A single-cell approach to metabolomics links metabolic profiles to cellular identity.

Algorithms trained to interpret microscope data can greatly extend the information that can be derived from the resulting images, or even optimize how imaging experiments are conducted.

Neurochemistry sensors for brain research and life with a collaborative frame of mind.

Conferring optical sectioning capabilities on light field microscopy improves signal-to-noise ratio while maintaining high imaging speed.

Fluorescent proteins can bind amyloid fibrils formed from natural peptides and proteins.

An integrative modeling framework enables cross-validation of existing E. coli datasets and prediction of uncharacterized parameters.

A machine learning model uses autofluorescence of key metabolites to predict T cell activation state.

Engineered intrinsically disordered proteins can induce phase separation and be used to modulate cellular function.