News & Comment

The US elections take place in a little over a month. How its citizens vote will have a major impact on the scientific community and on the integrity of the scientific enterprise in the United States.

Frugally built technology to study the ocean’s microbes, and engineering for societal good.

To better study human neurodevelopment, researchers advance organoids as brain models.

Addition of a second constriction to CsgG-family nanopores improves the accuracy of homopolymer sequencing.

Stdpopsim facilitates realistic population genetics simulations with a catalog of widely used models.

A protein degradation platform enables the targeted depletion of extracellular and membrane-bound proteins.

Stem-cell-derived organoids reproduce the in vivo secretory and functional properties of the choroid plexus.

We distributed an informal questionnaire to learn from scientists about their professional use of WeChat. We share some of their answers and discuss the multipurpose platform offered by WeChat.

BRICseq provides access to brain-wide connectivity and can be combined with functional and transcriptomic studies for a comprehensive view of neuronal circuitry.

“I have no idea what’s awaiting me, or what will happen when this all ends. For the moment I know this: there are sick people and they need curing.” ―Albert Camus, The Plague

With advanced approaches to sample preparation and data analysis, scientists doing cryo-EM are starting to infer molecular movements from samples that are, literally, frozen.

A new way to see actin in action, hearing as others don’t, and saved by the guitar.

Tethering fluorescent proteins to ribosomes clears up background signals when imaging neural circuits.

Intravital three-dimensional bioprinting enables the biofabrication of constructs in a pre-existing 3D matrix, such as inside tissues of live animals.

RIC-seq enables in situ mapping of intra- and intermolecular RNA–RNA interactions.

Direct imaging of carbohydrates using electrospray ion beam deposition and scanning tunneling microscopy.

We’ve made some recent updates to our various content type offerings at Nature Methods. Here is a cheat sheet.

barRNAseq allows detailed explorations of signaling pathways that control embryonic differentiation.