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Researchers generated a high-resolution snapshot of the epigenome of Arabidopsis thaliana by constructing and integrating the methylome, transcriptome and small RNAome using next-generation sequencing.
A 3D laser scanning microscopy method requiring no moving parts promises to expand the in vivo study of fast neuronal signaling at cellular and subcellular levels.
Biologists are increasingly interested in single-molecule approaches. In this issue, a Focus provides a biologist's guide to this relatively new field, and two papers present advances in nanoscale visualization.
In less than five years the Nano/Bio Interface Center at the University of Pennsylvania has gone from an idea to a nationally funded nanotechnology center. A look inside reveals how they have taken a collaborative approach to technology development.