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Physician–scientists who become parents during their long period of training need additional funding and support for lactation, childcare and healthcare, to ensure an equitable workforce.
Brain insulin action, previously well studied in men, is now shown to improve peripheral insulin sensitivity during the follicular phase but not the luteal phase of the menstrual cycle.
Incretin-based drugs have demonstrated unprecedented efficacy in weight-loss trials, but ensuring that healthy body weight can be maintained is fundamental to sustainable good health.
Nature Medicine explores the latest translation and clinical research news, with results from a phase 2 clinical trial of zilebesiran from Alnylam and Roche.
External comparator arms should be used when investigating novel therapies for gastrointestinal stromal tumor and other rare tumors to facilitate drug testing and regulatory approvals.
Artificial intelligence tools usually aim to maximize predictive accuracy, but personalized measures of uncertainty, using new techniques such as conformal prediction, are needed for clinical artificial intelligence to realize its potential and improve human health.
First-line treatment with dabrafenib plus trametinib resulted in better clinical responses and lower toxicity than chemotherapy in children with BRAF V600E mutation and low-grade glioma.
Not involving communities throughout the research process may be attributable to prejudice and a failure to recognize privilege. The result is a loss for all involved.
Systematic reviews and meta-analyses are used by clinicians and policymakers to synthesize medical evidence, but they can amplify falsified or poor-quality clinical trial data. In this era of contested evidence, new approaches are needed.
Nature Medicine explores the latest translation and clinical research news, with results from a clinical trial of Novartis' discontinued gene therapy to restore fetal hemoglobin.
As healthcare systems perform better, their resource footprints have an increasingly negative impact on the environment and health — requiring innovative strategies to break this vicious cycle.
Grown from stem cells, the models recapitulate the hallmarks of post-implantation human embryos up to day 14, opening new avenues of research into early human development.
We asked leading researchers to share new discoveries about SARS-CoV-2 and COVID-19, from how the virus spreads and the risk of long COVID to the impact of vaccines and masks.
Produce prescriptions improved fruit and vegetable intake, reduced food insecurity and improved biomarkers of cardiometabolic health, according to a large, retrospective, US-based study.
A monumental challenge to scientists due to its repetitive sequences, the human Y chromosome has now been fully sequenced — revealing new structures in regions critical for fertility.