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The pandemic has limited access to endoscopy screening for patients with Barrett’s esophagus, but a new biomarker-based method could help prioritize patients based on cancer risk.
Built-in decision thresholds for AI diagnostics are ethically problematic, as patients may differ in their attitudes about the risk of false-positive and false-negative results, which will require that clinicians assess patient values.
Combinations of cardiovascular medications taken in a single pill — known as polypills — are effective but not widely used, requiring a global shift from physicians, regulators and drug developers.
A US-based study highlights widening disparities in air quality, with racial/ethnic minorities and low-income groups exposed to higher levels of pollution.
The Glasgow Climate Pact reaffirms countries’ commitments to limiting global heating to 1.5 °C, but without prioritizing health, equity and multisectoral engagement within climate action, the health of the planet and the future of humanity remain at grave risk.
Microbiome alterations have been associated with autism, but a new study suggests that this may be a consequence of autism-related dietary preferences, rather than a causal factor.
COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity.
If used correctly, patient-reported outcomes can provide preliminary evidence of efficacy and tolerability from a patient perspective, as well as supporting regulatory review.
Medical discoveries have been shared at an unprecedented pace during the COVID-19 pandemic, but so have fraudulent studies, which has led to worries about scientific integrity.
The passe sanitaire increased levels of vaccination, but to a lower extent among the most vulnerable, and did not reduce vaccine hesitancy itself, showing the importance of outreach to underserved communities and the potential limits of mandatory vaccination policies.
CAR-T cell therapies may represent a viable treatment for relapsed or refractory disease, but further studies will be needed to refine patient selection.
People with HIV who delay initiation of anti-retroviral therapy have permanent loss of memory T cells in the skin, which may explain their increased risk of skin cancer.
Parents give consent for their children’s health data to be used in research, but what happens when the children reach adulthood, and how can researchers keep families involved in the meantime?