Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Fred Ramsdell and Alexander Rudensky revisit the discovery of the Foxp3 gene and its foundational role in the differentiation and function of regulatory T cells.
Immunologists used to avoid metabolism, but that is no longer possible. Now that we must talk about it, how can we do so in a way that enhances and clarifies our understanding of the role metabolism plays in the immune response?
Despite new vaccines, therapeutics, and the extensive lessons learned from the West African Ebola outbreak, the DRC’s 2018–2020 outbreak has taken nearly 20 months to bring under control. This Comment explores some of the factors that have made this outbreak so complex.
Climate change is already affecting vector-borne disease transmission and spread, and its impacts are likely to worsen. In the face of ongoing climate change, we must intensify efforts to prevent and control vector-borne diseases.
Climate change can trigger a sequence of events of significant magnitude with consequences for waterborne diseases. Heavy rainfall, flooding and hot weather are associated with waterborne diseases, but early warning systems could intercept these cascading risks.