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  • Focus |

    An overview, three review articles and two personal essays discuss the identification and function of transcription factors that regulate the differentiation of lymphocyte lineages.

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    A comprehensive overview and four review articles discuss the functions of plant and animal innate immune system receptors in the context of pathogen recognition and other immune functions.

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    Five especially commissioned articles that discuss how immune cells communicate in selected tissue microenvironments.

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    A comprehensive overview, and three review articles examine how inflammation is dampened by the immune system.

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    To celebrate our 5 years of serving the immunology community, we have assembled a collection of papers that illustrates the breadth of subject matter our pages cover.

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    Four review articles and a perspective examine the biology and function of regulatory T cells.

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    A comprehensive overview, three review articles and a perspective examine how the innate immunity influences the outcome of the adaptive immune response.

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    Immune surveillance requires constant sampling of cellular peptides by T cells. Here, we present four reviews describing the generation of antigenic peptide epitopes and the cellular enzymes responsible.

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    A comprehensive overview and four review articles that demystify the molecular mechanisms underlying lymphocytes' unique recombination events and specific gene expression programs.

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    This joint web focus with Nature Reviews Immunologyexamines recent inroads into how cell death pathways intersect with the immune system during both development and disease.

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    A series of comprehensive reviews examining mechanisms of immune escape. The juxtaposition of tumor with microbial immune evasion reveals the many parallels between the different systems.

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    The hematopoietic stem cells that reside in our bone marrow might aptly be described as our source of vitality. This focus contains an analysis of progress and news in hematopoietic stem cell research.