Commentary in 2009

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  • Data management has been neglected but should be made an integral activity in all research laboratories. Chaussabel and colleagues discuss how to implement this at the bench.

    • Damien Chaussabel
    • Hideki Ueno
    • Charles Quinn
    Commentary
  • The Science Gallery, Trinity College Dublin, recently held an exhibition called “INFECTIOUS: STAY AWAY” that used art to illustrate infection and immunity. Luke O'Neill talks to one of the artists, Gordana Novakovic, about her involvement in this project.

    • Luke A J O'Neill
    • Cliona O'Farrelly
    Commentary
  • By identifying gene products whose knockdown is associated with phenotypic changes, large-scale RNA-mediated interference screens have demonstrated previously unknown components of biological pathways. This commentary provides general guidelines for using such screens to answer questions of immunological interest.

    • Sonia Sharma
    • Anjana Rao
    Commentary
  • The US National Institute of Allergy and Infectious Diseases convened a workshop of malaria investigators and immunologists to foster collaborations and attract more immunologists into malaria research. Discussions highlighted research gaps and underscored the incomplete understanding of basic immune mechanisms that contribute to the pathogenesis of or protection against malaria.

    • Alison Deckhut Augustine
    • B Fenton Hall
    • Anthony S Fauci
    Commentary
  • How have women fared at Harvard since the events of four years ago? Here, Judy Lieberman and Laurie Glimcher reflect on progress made and barriers still to be breached.

    • Laurie H Glimcher
    • Judy Lieberman
    Commentary
  • Is it possible to return from the industrial sector back to academia? Although academic scientists have traditionally perceived this to be akin to winning the Nobel prize, the personal experience of Ross Kedl suggests that the reality is something quite different altogether.

    • Ross M Kedl
    Commentary
  • Type 1 diabetes is an immune-mediated disease in which pancreatic insulin-producing beta cells are damaged and destroyed. Animal models have served a prominent function in the development of the present ideas of pathogenesis and approaches to therapy. This commentary addresses the utility and limitations of these models for facilitating the 'translation' of immunology research into clinical applications.

    • Matthias von Herrath
    • Gerald T Nepom
    Commentary