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Our ability to map trait-associated regulatory variation still vastly exceeds the prospects for dissecting allele-specific effects on gene expression and activity in vivo in relevant tissues and organs. A small number of intensive investigations into functional variants should pave the way for scaleable strategies using high-throughput techniques and genomic data integration.
We welcome our new sister journal Nature Plants and the increased commitment to the plant science community that it represents. This is an opportunity for Nature Genetics to emphasize the use of genetic and genomic tools and resources in discovering new plant biology and solving major agricultural challenges.