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The impact of the papers we publish depends increasingly on the data they describe. In insisting on data access for referees and readers, we prioritize scientific integrity above all and place the interests of research participants before impact.
Whereas once it was only possible to generate reference genome sequences one at a time, it is now feasible to design genomic experiments to maximize functional comparisons and contrasts among many genomes. Investigating the diversity of a number of related parasite genomes and their transcriptomes in multiple contexts increasingly shows us ways to intervene in the ecological and evolutionary strategies of pathogens.
Familiarity with developments in all areas of genetics—from the trained intuition of dysmorphology to algorithms for SNP calling in next-generation sequencing—is extraordinarily productive in research and clinical translation. Actively organized conferences modeled on the recent European Society of Human Genetics (ESHG) meeting in Nuremberg go a long way in preparing the field for future success.