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Nature's pride in its survival this far should not be mistaken for evidence that the future can prudently be an extrapolation of the past. There are challenges and opportunities ahead.
Prizes of £500 are awarded to Dr Paul Grant and Dr Dan Hultmark, each of whom has provided Nature with an outstanding News and Views article during its 125th anniversary year.
Structural insight into the trimeric organization of the human mannose-binding protein sheds light on the workings of the non-clonal, innate immune response in vertebrates.