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Volume 248 Issue 5451, 26 April 1974

Opinion

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  • In recent years there has been a marked change in the way the British government is advised about scientific affairs. John Gribbin discusses this change, and the position of science in industrialised society today, in the light of the recent appointment of Dr Robert Press to coordinate the government's scientific advice.

    Opinion
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International News

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News & Views

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Article

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Letter

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Molecular Biology

  • Francis Crick reviews the papers published 21 years ago on the structure of DNA and the reaction to them.

    • Francis Crick
    Molecular Biology
  • Linus Pauling reviews his work on the molecular basis of biological specificity and remembers his erroneous conception of a three-chain helix structure for DNA in 1952.

    • Linus Pauling
    Molecular Biology
  • Dr Gurdon discusses the introduction of purified macromolecules, such as nucleic acids and proteins, into living cells in controlled amounts and in such a way that they function normally.

    • J. B. Gurdon
    Molecular Biology
  • In remembering, without nostalgia, the dawn of molecular biology, Dr Chargaff deplores the loss of innocence that science has suffered in his lifetime.

    • Erwin Chargaff
    Molecular Biology
  • “And now the announcement of Watson and Crick about DNA. This is for me the real proof of the existence of God”. (Salvador Dali, 1964).

    • Gunther S. Stent
    Molecular Biology
  • “Nucleic acids bulk so large in the composition of cells that it seems certain that these substances are involved in some important biological functions. Nevertheless, with one exception [bacterial transformation], there has been no proof of a specific biological function mediated by one of these palynucleotides; no enzyme, hormone, vitamin, or even vague ‘growth substance’ has been found to be a nucleic acid.”

    • Robert Olby
    Molecular Biology
  • “Much has been written about the philosophical consequences of molecular biology. I think it is now clear what the entire enterprise is about. We are looking at a rather special part of the physical universe which contains special mechanisms none of which conflict at all with the laws of physics.”

    • Sydney Brenner
    Molecular Biology
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Letter

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Book Review

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Matters Arising

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Announcements

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