Reviews & Analysis

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  • Long-acting drug delivery formulations enable sustained and prolonged drug release at the site of action or for systemic delivery, overcoming the need for frequent and repeated drug administration. This Review discusses US Food and Drug Administration (FDA)-approved long-acting drug delivery formulations, highlighting different slow-release mechanisms and delivery platforms, and the materials used to achieve them.

    • Wei Li
    • Jie Tang
    • Mark R. Prausnitz
    Review Article
  • Microplastic is a complex contaminant causing great concern in society. This Review examines the properties of microplastic particles compared with natural particles in the environment and discusses methods of assessing the risks to humans and the environment.

    • Albert A. Koelmans
    • Paula E. Redondo-Hasselerharm
    • Merel Kooi
    Review Article
  • Plastics support modern life but are also associated with environmental pollution. This Review discusses technologies for the production and recycling of bioplastics as part of a more sustainable and circular economy.

    • Jan-Georg Rosenboom
    • Robert Langer
    • Giovanni Traverso
    Review Article
  • The design of superionic conductors necessitates a fundamental understanding of how to invoke fast ion transport in the solid state. This Review discusses the role of framework anion rotational dynamics in enhancing cation diffusion through the paddle-wheel mechanism and its exploitation at room temperature.

    • Zhizhen Zhang
    • Linda F. Nazar
    Review Article
  • Nanoreactors that isolate chemical precursors within a confined space are promising tools for synthesizing nanoparticles. This Review unifies the many classes of solution-based and substrate-confined nanoreactors, evaluating their current synthetic capabilities and their potential for solving future challenges in nanoparticle synthesis.

    • Jordan H. Swisher
    • Liban Jibril
    • Chad A. Mirkin
    Review Article
  • Centrifugal and/or shear forces induced by rotary motion can drastically alter outcomes of chemical experiments and processes. This Review surveys rotary systems in which such forces control self-organization phenomena, materials synthesis or even chemical reactivity at molecular and macromolecular scales.

    • Bartosz A. Grzybowski
    • Yaroslav I. Sobolev
    • Barbara Mikulak-Klucznik
    Review Article