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  • Special |

    In recent years we have seen continued growth in the field of precision medicine. Developments in technology have yielded the ability to detect many tumour-relevant entities in blood samples, including circulating tumour DNA, RNA, extracellular vesicles, tumour cells and tumour-educated immune cells. This Collection on Liquid biopsy features Special Issue content guest edited by Professor Angela Cox (University of Sheffield, UK,) and Professor Klaus Pantel (University Medical Center Hamburg-Eppendorf, Germany) and includes a curated set of research articles and commissioned content from leading researchers.

    Image: curlymary / stock.adobe.com

  • Special |

    Key issues in optimum cancer management and prevention may be greatly aided by artificial intelligence (AI), particularly deep learning and reinforcement learning methods. This AI Applied to Cancer collection, curated by Faraz Janan (Imperial College London, UK) with the assistance of Louise Wilkinson (Oxford Breast Imaging Centre, UK), provides a collection of articles and commissioned content highlighting the state-of-the-art available AI models and techniques, limitations related to the AI applications in a clinical setup, and patient perspectives and the future of AI in cancer management.

    Image: metamorworks/ Getty images / iStock

  • Special |

    The incurability of metastatic cancer is currently an unmet clinical need which needs to be addressed. This Collection on Metastasis highlights the ongoing challenges in the field and research being undertaken to more thoroughly understand models of metastasis, disrupt the metastatic cascade, and improve treatment outcomes for patients. Featuring Special Issue content that has been curated by Suzanne Fuqua (Baylor College of Medicine, USA), this Collection contains a selection of articles and commissioned content from leading researchers, to present a broad-scope view of current research focal points and explore future directions of cancer metastasis.

    Image: David A. Litman/Shutterstock
    Open for submissions

  • Special |

    Metabolic perturbations are a hallmark of cancer. Unique bioenergetic and biosynthetic alterations enable growth and metastasis in a nutrient-poor environment and understanding these modified pathways has been a key focus of research so far. We are now at a position where we need to develop these findings into preclinical and clinical outcomes, and this Special Issue on Cancer Metabolism highlights the ongoing challenges in the field. Curated by Professor Adrian Harris (University of Oxford) and Dr Christian Frezza (University of Cambridge), the Special Issue contains a selection of articles and commissioned content that provide insights into a variety of ongoing questions in oncometabolism, to help drive the translation of these findings towards the clinic.

    Image: Bill Longcore/Science Source

  • Special |

    This Special Edition on Immunotherapy contains a selection of articles, commissioned content and videos that provide valuable insight into immunotherapy design, stratification and toxicity management.

    Image: DNA Illustrations/Science Source