Biotransformation of xenobiotics by gut microbiota can impact bioactivity and toxicity. A new study shows how hydrogen sulfide generated by gut microbes reduces azo compounds extracellularly and non-enzymatically.
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Kamrad, S., Lindell, A.E. & Patil, K.R. Gut reaction: it’s not all about enzymes. Nat Metab 4, 1219–1220 (2022). https://doi.org/10.1038/s42255-022-00637-2
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DOI: https://doi.org/10.1038/s42255-022-00637-2