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Phage therapy

Armed phages are heading for clinical trials

Nature Microbiology volume 8, pages 1191–1192 (2023)Cite this article

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A combination of four phages engineered with a CRISPR–Cas payload can reduce the burden of Escherichia coli infections in animal models without inducing the host immune response.

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Fig. 1: Development of SNIPR001.

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Authors and Affiliations

  1. School of Life Sciences, University of Warwick, Coventry, UK

    Jessica Maree Lewis & Antonia P. Sagona

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  1. Jessica Maree Lewis
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  2. Antonia P. Sagona
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Correspondence to Jessica Maree Lewis or Antonia P. Sagona.

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The authors declare no competing interests.

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Lewis, J.M., Sagona, A.P. Armed phages are heading for clinical trials. Nat Microbiol 8, 1191–1192 (2023). https://doi.org/10.1038/s41564-023-01415-w

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