Biopolymer matrices can modulate the transcriptomic profiles of stem-cell-derived neurons in 3D culture to make them resemble cells in specific brain regions, developmental stages and disease conditions.
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Werner, C. Matrix-mediated modulation of neuron identity. Nat Biomed Eng 2, 473–474 (2018). https://doi.org/10.1038/s41551-018-0270-6
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DOI: https://doi.org/10.1038/s41551-018-0270-6