Neuronal physiology articles from across Nature Portfolio

Kalium channelrhodopsins (KCRs) are promising tools for optogenetic silencing. Here, the authors show that KCRs inhibit cellular excitability in flies, worms, and fish, establishing them as first-line tools for inhibiting diverse types of excitable cells.

Ning-long Xu discusses a 1999 paper that outlined a mechanism by which cortical pyramidal neurons integrate layer-specific inputs.

Blood pressure pulsations modulate the activity of neurons in the rodent olfactory bulb via the mechanosensitive ion channel PIEZO2

A basket-like device records the electrical activity of neural organoids over months of maturation.

A study indicates that different mechanisms of ATP production predominate in different cellular subcompartments in neurons.

A new biotinylation-based approach identifies previously unknown cell surface proteins of the axonal initial segment (AIS) and shows a role for contactin-1 in assembly of the AIS extracellular matrix.