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Response to Analysis of serum 25-hydroxyvitamin D levels involves taking into account several confounding factors

European Journal of Clinical Nutrition volume 76, page 1490 (2022)Cite this article

Subjects

According to the letter published by Dr. Lu-Lu Zhai and collaborators [1], we can comments as follows.

This study considered three areas of Chile that have different average temperature ranges and are located in different latitudes (Antofagasta 23.6524° S 70.3954° W; Santiago 33.4569° S 70.6483° W; Concepción 36.827° S 73.0498° W). The study was conducted in late fall through early spring. During May to September 2018, cloudiness in Santiago (in the plain, 570 m above sea level) was 47–58%, minimum temperatures 7 °C maximum 23 °C, cloudiness in Antofagasta (on the coast) was 73–84%, minimum temperatures 13 °C maximum 24 °C and cloudiness in Concepción (at the coast) was 40–60, minimum temperatures 6 °C maximum 16 °C. These two conditions make the population wear warm clothing with little exposure to the sun. However, the exact sun exposure time was not determined in this study.

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References

  1. Zhai LL, Chen CX, Zhan CH, You GW, Chen QL, Tang ZG. Analysis of serum 25-hydroxyvitamin D levels involves taking into account several confounding factors. Eur J Clin Nutr. 2022. https://doi.org/10.1038/s41430-022-01098-2. Epub ahead of print. PMID: 35149832.

  2. Degerud E, Hoff R, Nygård O, Strand E, Nilsen DW, Nordrehaug JE, et al. Cosinor modelling of seasonal variation in 6 25- hydroxyvitamin D concentrations in cardiovascular patients in Norway. Eur J Clin Nutr. 2016;70:517–22. https://doi.org/10.1038/ejcn.2015.200.

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  3. MINSAL. National Food Consumption Survey (ENCA) Chile 2014. https://www.minsal.cl/sites/default/files/ENCA-INFORME_FINAL.pdf. 2014.

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Authors and Affiliations

  1. Micronutrients Laboratory, INTA, University of Chile, Santiago, Chile

    Francisco Pérez-Bravo & Miguel Arredondo-Olguín

  2. School of Nutrition and Dietetics, Finis Terrae University, Santiago, Chile

    Oscar Castillo-Valenzuela

Authors
  1. Francisco Pérez-Bravo
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  2. Miguel Arredondo-Olguín
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  3. Oscar Castillo-Valenzuela
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Contributions

Conceptualization, FPB and OCV; Formal analysis FPB, MAO, OCV, Investigation, FPB and OCV; Writing – original draft, FPB and OCV Writing – review & editing, MAO.

Corresponding author

Correspondence to Oscar Castillo-Valenzuela.

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The authors declare no competing interests.

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Pérez-Bravo, F., Arredondo-Olguín, M. & Castillo-Valenzuela, O. Response to Analysis of serum 25-hydroxyvitamin D levels involves taking into account several confounding factors. Eur J Clin Nutr 76, 1490 (2022). https://doi.org/10.1038/s41430-022-01132-3

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  • DOI: https://doi.org/10.1038/s41430-022-01132-3

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