This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Identification of a novel role for TL1A/DR3 deficiency in acute respiratory distress syndrome that exacerbates alveolar epithelial disruption
Respiratory Research Open Access 11 July 2023
Access options
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Chang SH, Choi BY, Choi J, Yoo JJ, Ha YJ, Cho HJ, et al. Baseline serum interleukin-34 levels independently predict radiographic progression in patients with rheumatoid arthritis. Rheumatol Int. 2015;35:71–9.
Moon SJ, Hong YS, Ju JH, Kwok SK, Park SH, Min JK. Increased levels of interleukin 34 in serum and synovial fluid are associated with rheumatoid factor and anticyclic citrullinated peptide antibody titers in patients with rheumatoid arthritis. J Rheumatol. 2013;40:1842–9.
Van Raemdonck K, Umar S, Palasiewicz K, Volin MV, Elshabrawy HA, Romay B, et al. Interleukin-34 reprograms glycolytic and osteoclastic rheumatoid arthritis macrophages via syndecan 1 and macrophage colony-stimulating factor receptor. Arthritis Rheumatol. 2021;73:2003–14.
Yu T, Chaganty B, Lin L, Xing L, Ramakrishnan B, Wen K, et al. VIS832, a novel CD138-targeting monoclonal antibody, potently induces killing of human multiple myeloma and further synergizes with IMiDs or bortezomib in vitro and in vivo. Blood Cancer J. 2020;10:110.
Bezie S, Freuchet A, Serazin C, Salama A, Vimond N, Anegon I, et al. IL-34 actions on FOXP3(+) tregs and CD14(+) monocytes control human graft rejection. Front Immunol. 2020;11:1496.
Wang B, Tang Y, Sun X, Ouyang X, Li H, Wei J, et al. Increased IL-6 expression on THP-1 by IL-34 stimulation up-regulated rheumatoid arthritis Th17 cells. Clin Rheumatol. 2018;37:127–37.
Li X, Lei Y, Gao Z, Zhang B, Xia L, Lu J, et al. Effect of IL-34 on T helper 17 cell proliferation and IL-17 secretion by peripheral blood mononuclear cells from rheumatoid arthritis patients. Sci Rep. 2020;10:22239.
Foucher ED, Blanchard S, Preisser L, Descamps P, Ifrah N, Delneste Y, et al. IL-34- and M-CSF-induced macrophages switch memory T cells into Th17 cells via membrane IL-1alpha. Eur J Immunol. 2015;45:1092–102.
Chang EJ, Lee SK, Song YS, Jang YJ, Park HS, Hong JP, et al. IL-34 is associated with obesity, chronic inflammation, and insulin resistance. J Clin Endocrinol Metab. 2014;99:E1263–71.
Zorena K, Jachimowicz-Duda O, Waz P. The cut-off value for interleukin 34 as an additional potential inflammatory biomarker for the prediction of the risk of diabetic complications. Biomarkers. 2016;21:276–82.
Acknowledgements
The authors would like to thank Balaji B. Ganesh, Director of the Flow Cytometry Core at the University of Illinois at Chicago, and Pei-Yu Wu for their excellent scientific advice. We thank Drs. Alexander and Colonna for kindly providing us with SDC-1−/− and IL-34−/− mice.
Funding
This work was supported in part by awards from the Department of Veteran’s Affairs MERIT Award BX002286, the Innovative Research Award from the Rheumatology Research Foundation (RRF), the National Institutes of Health NIH AI147697, the National Psoriasis Foundation (NPF), the Pfizer Investigator-Initiated Research (IIR) Program and the Chicago Biomedical Consortium (CBC) Accelerator Award.
Author information
Authors and Affiliations
Contributions
AM, KvR, and SS made substantial contributions to the study concept and design. AM, RS, BZ, KvR, KP, MVV, and SS contributed to data acquisition. AM, RS, BZ, KvR, KP, DPM, MVV, and SS contributed to the analysis and interpretation of the data. AM, RS, BZ, KvR, KP, DPM, MVV, and SS drafted the article or revised it critically for important intellectual content. AM, RS, BZ, KvR, KP, DPM, MVV, and SS approved the final version to be published. AM, RS, BZ, KvR, KP, DPM, MVV, and SS agree to the accountability for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. SS had full access to all data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Supplementary information
Rights and permissions
About this article
Cite this article
Meyer, A., Sienes, R., Zanotti, B. et al. Dysregulation of IL-34 ligation to SDC-1 mitigates collagen-induced arthritis. Cell Mol Immunol 19, 1070–1072 (2022). https://doi.org/10.1038/s41423-022-00886-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41423-022-00886-x
This article is cited by
-
Identification of a novel role for TL1A/DR3 deficiency in acute respiratory distress syndrome that exacerbates alveolar epithelial disruption
Respiratory Research (2023)
-
Metabolic reprogramming by Syntenin-1 directs RA FLS and endothelial cell-mediated inflammation and angiogenesis
Cellular & Molecular Immunology (2023)