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References
Eaton SE, Kaczmarek J, Mahmood D, McDiarmid AM, Norarfan AN, Scott EG, et al. Exploiting dietary fibre and the gut microbiota in pelvic radiotherapy patients. Br J Cancer. 2022;127:2087–98.
Vodnar DC, Calinoiu LF, Mitrea L. Editorial: exploiting the effect of dietary fibre on the gut microbiota in patients with pelvic radiotherapy. Br J Cancer. 2022;127:1575–6.
Murray J, Cruickshank C, Bird T, Bell P, Braun J, Chuter D, et al. PEARLS—a multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation. Clin Transl Radiat Oncol. 2022;37:130–6.
Reis Ferreira M, Khan A, Thomas K, Truelove L, McNair H, Gao A, et al. A phase I/II dose escalation study of the use of intensity modulated radiotherapy (IMRT) to treat the prostate and pelvic nodes in patients with prostate cancer. Int J Radiat Oncol Biol Phys. 2017; http://linkinghub.elsevier.com/retrieve/pii/S0360301617336556.
Hauer-Jensen M, Denham JW, Andreyev HJN. Radiation enteropathy—pathogenesis, treatment and prevention. Nat Rev Gastroenterol Hepatol. 2014;11:470–9.
Queen J, Domingue JC, White JR, Stevens C, Udayasuryan B, Nguyen TTD, et al. Comparative analysis of colon cancer-derived fusobacterium nucleatum subspecies: inflammation and colon tumorigenesis in murine models. mBio. 2022;13:e0299121.
Wedlake L, Shaw C, McNair H, Lalji A, Mohammed K, Klopper T, et al. Randomized controlled trial of dietary fiber for the prevention of radiation-induced gastrointestinal toxicity during pelvic radiotherapy. Am J Clin Nutr. 2017;106:849–57.
Reis Ferreira M, Andreyev J, Mohammed K, Truelove L, Gowan SM, Li J, et al. Microbiota and radiotherapy-induced gastrointestinal side-effects (MARS) study: a large pilot study of the microbiome in acute and late radiation enteropathy. Clin Cancer Res. 2019;25:6487–500.
Ferreira MR, Sands CJ, Li JV, Andreyev JN, Chekmeneva E, Gulliford S, et al. Impact of pelvic radiation therapy for prostate cancer on global metabolic profiles and microbiota-driven gastrointestinal late side effects: a longitudinal observational study. Int J Radiat Oncol Biol Phys. 2021;111:1204–13.
Guo H, Chou WC, Lai Y, Liang K, Tam JW, Brickey WJ, et al. Multi-omics analyses of radiation survivors identify radioprotective microbes and metabolites. Science. 2020;370:eaay9097.
Levy A, Stedman A, Deutsch E, Donnadieu F, Virgin HW, Sansonetti PJ, et al. Innate immune receptor NOD2 mediates LGR5+ intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation. Proc Natl Acad Sci USA. 2020;117:1994–2003.
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MRF: conceptualisation, drafting of paper, review, approval of the final manuscript; JNA: conceptualisation, drafting of paper, review and approval of the final manuscript, LW: conceptualisation, drafting of paper, review and approval of the final manuscript, DPD: conceptualisation, drafting of paper, review and approval of the final manuscript. All authors agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
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Ferreira, M.R., Andreyev, J.N., Wedlake, L. et al. Comment on “Exploiting dietary fibre and the gut microbiota in pelvic radiotherapy patients”. Br J Cancer 128, 711–712 (2023). https://doi.org/10.1038/s41416-023-02163-8
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DOI: https://doi.org/10.1038/s41416-023-02163-8