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An egg a day keeps kernicterus away

Pediatric Research (2024)Cite this article

Neonatal hyperbilirubinemia is a common occurrence in newborns, and timely and effective management of severe neonatal hyperbilirubinemia (SNH) by phototherapy (PT), and more recently double PT, the current golden standard treatment for reducing total serum bilirubin (TSB), is crucial for avoiding childhood disability (kernicterus spectrum disorder - KSD), or even death (reviewed in1).

Despite being an apparently easy condition to manage, kernicterus still occurs worldwide, and a dichotomy in its management exists. While unavailability and/or inefficacy of diagnosis and proper therapy is the major cause of kernicterus and death in low-incoming countries (LIC), the medical advances, leading to increasingly premature newborns to survive, is a new challenge in the industrialized Nations (IN) (reviewed in1).

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References

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Funding

This work was supported by institutional funds from the Fondazione Italiana Fegato and was not supported by extramural sources.

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Authors and Affiliations

  1. Liver Brian Unit “Rita Moretti”, Fondazione Italiana Fegato – Onlus, AREA Science Park - Basovizza Campus, 34149, Trieste, Italy

    Silvia Gazzin & Claudio Tiribelli

Authors
  1. Silvia Gazzin
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  2. Claudio Tiribelli
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All Authors have contributed to conception, interpretation, writing the commentary and approved the final version.

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Correspondence to Claudio Tiribelli.

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Gazzin, S., Tiribelli, C. An egg a day keeps kernicterus away. Pediatr Res (2024). https://doi.org/10.1038/s41390-024-03103-9

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