Dysreglulated methylation of lysine residues on histone molecules has been implicated in the development of cancer. In their Review on page 917, Helin and colleagues first highlight the links between histone lysine demethylases and cancer, and then discuss recent small-molecule inhibitors.

Here in Table 1 we highlight patent applications published in the past 2 years related to histone demethylases. Data were researched using the Espacenet database.

Table 1 Recent patent applications related to histone lysine demethylases
Full size table