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Daily nocturnal hemodialysis—a paradigm shift worthy of disrupting current dialysis practice

Nature Clinical Practice Nephrology volume 4, pages 602–603 (2008)Cite this article

Various strategies have been considered in attempts to improve the outcomes of patients on dialysis, including increasing dialysis dose, using alternative depuration methods, changing dialysis schedules and focusing on preventing or treating specific comorbidities and complications. This paper will discuss the first three strategies.

Two well-designed, randomized controlled trials (RCTs; the HEMO [Hemodialysis] study and ADEMEX [ADEquacy of peritoneal dialysis in MEXico]) did not support the hypothesis that increased dialysis dose decreases mortality in patients on thrice-weekly hemodialysis or continuous ambulatory peritoneal dialysis.1,2

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Author notes

  1. Humber River Regional Hospital, University of Toronto, 200 Church Street, Weston, ON M9N 1N8, Canada a.pierratos@utoronto.ca

Authors and Affiliations

  1. A Pierratos is a Nephrologist at the Humber River Regional Hospital, and Associate Professor of Medicine at the University of Toronto, ON, Canada.,

    Andreas Pierratos

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  1. Andreas Pierratos
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The author declares no competing financial interests.

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Pierratos, A. Daily nocturnal hemodialysis—a paradigm shift worthy of disrupting current dialysis practice. Nat Rev Nephrol 4, 602–603 (2008). https://doi.org/10.1038/ncpneph0938

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