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Information technology and the role of WMDA in promoting standards for international exchange of hematopoietic stem cell donors and products

Bone Marrow Transplantation volume 45, pages 839–842 (2010)Cite this article

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Abstract

Nearly half of the unrelated hematopoietic SCTs facilitated worldwide involves an exchange of products between countries. The process is information intensive and requires coordination through regional hubs of complex data transactions of demographic, clinical and genetic information, laboratory samples and results. Each registry has developed its own unique systems for representing data and process leading to transplantation. The WMDA Information Technology Working Group was formed in the autumn of 2001 as a forum to discuss and develop standards for information technology (IT) in support of hematopoietic stem cell registries. Its membership includes experts in IT from the WMDA member registries. The group has focused its standardization efforts on three areas:

  • Standardized reference data sets for validation and plausibility controls for HLA and other data domains

  • Matching algorithm standards for determining histocompatibility

  • Communication standards between registries.

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References

  1. Bochtler W, Maiers M, Oudshoorn M, Marsh SGE, Raffoux C, Mueller C et al. World Marrow Donor Association guidelines for use of HLA nomenclature and its validation in the data exchange among hematopoietic stem cell donor registries and cord blood banks. Bone Marrow Transplant 2007; 39: 737–741.

    Article  CAS  PubMed  Google Scholar 

  2. Marsh SGE, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA et al. Nomenclature for factors of the HLA system, 2004. Tissue Antigens 2005; 65: 301–369.

    Article  CAS  PubMed  Google Scholar 

  3. Robinson J, Malik A, Parham P, Bodmer JG, Marsh SGE . IMGT/HLA—a sequence database for the human major histocompatibility Complex. 2000; 55: 28–287. http://hla.alleles.org/wmda/index.html.

  4. Bochtler W, Beth M, Marsh SGE, Mueller CR . HLACORE—a comprehensive low level HLA library for programmers. Hum Immunol 2005; 66: 49.

    Article  Google Scholar 

  5. emdisnet Available from 2010. http://www.emdis.net.

  6. BMDW.org 2010 Leiden: Bone Marrow Donors Worldwide; c1988 [updated 26 September 2007; cited 18 October 2007]. Total number of stem cell donors and cord blood units; [about 2 screens]. Available from http://www.bmdw.org/index.php?id=statistics_all.

  7. Müller CR . Computer applications in the search for unrelated stem cell donors. Transpl Immunol 2002; 10: 227–240.

    Article  PubMed  Google Scholar 

  8. Baouz A, Raffoux C . EMDIS: European Marrow Donor Information System. Comput Methods Programs Biomed 1994; 45: 45–46.

    Article  CAS  PubMed  Google Scholar 

  9. ESTER 2010 Available from http://www.steinersw.eu/en/ester.html.

  10. EMDIS Implementation Matrix 2010 Available from: http://www.czechbmd.cz/matrix/.

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Authors and Affiliations

  1. Bioinformatics Research, National Marrow Donor Program, Minneapolis, MN, USA

    M Maiers

  2. Europdonor Foundation, Leiden, The Netherlands

    J N A Bakker

  3. ZKRD Zentrales Knochenmarkspender-Register Deutschland, Ulm, Germany

    W Bochtler, H-P Eberhard, C Müller & H-G Rist

  4. Anthony Nolan Research Institute and Cancer Institute, University College London, London, UK

    S G E Marsh

Authors
  1. M Maiers
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  2. J N A Bakker
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  3. W Bochtler
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  4. H-P Eberhard
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  5. S G E Marsh
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  6. C Müller
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  7. H-G Rist
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on behalf of the Information Technology Working Group (ITWG) of the WMDA

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Correspondence to M Maiers.

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The authors declare no conflict of interest.

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Maiers, M., Bakker, J., Bochtler, W. et al. Information technology and the role of WMDA in promoting standards for international exchange of hematopoietic stem cell donors and products. Bone Marrow Transplant 45, 839–842 (2010). https://doi.org/10.1038/bmt.2010.29

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  • DOI: https://doi.org/10.1038/bmt.2010.29

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