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| Open AccessAn effective nano drug delivery and combination therapy for the treatment of Tuberculosis
- Mojgan Sheikhpour
- , Vincent Delorme
- & Shahin Pourazar
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| Open AccessMultiple-reaction monitoring (MRM) LC–MS/MS quantitation of venlafaxine and its O-desmethyl metabolite for a preclinical pharmacokinetic study in rabbits
- Abdul Aala Fazli
- , Bala Krishna Panigrahy
- & Nisar Ahmad Khan
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| Open AccessSimple, fast and reliable CE method for simultaneous determination of ciprofloxacin and ofloxacin in human urine
- Izabella Kośka
- , Krystian Purgat
- & Paweł Kubalczyk
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| Open AccessMutagenicity and safety pharmacology of a standardized antidiabetic polyherbal formulation
- Fadzilah Adibah Abdul Majid
- , Anis Fadhlina
- & Renuka Pillai
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| Open AccessCoriander (Coriandrum sativum L.) essential oil and oil-loaded nano-formulations as an anti-aging potentiality via TGFβ/SMAD pathway
- Mohamed A. Salem
- , Eman G. Manaa
- & Dalia I. Hamdan
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| Open AccessAlgorithmic multiscale analysis for the FcRn mediated regulation of antibody PK in human
- Dimitris G. Patsatzis
- , Shengjia Wu
- & Dimitris A. Goussis
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| Open AccessA universal methodology for reliable predicting the non-steroidal anti-inflammatory drug solubility in supercritical carbon dioxide
- Tahereh Rezaei
- , Vesal Nazarpour
- & Farzad Tat Shahdost
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| Open AccessNumerical investigation of ibuprofen removal from pharmaceutical wastewater using adsorption process
- Yan Cao
- , Ali Taghvaie Nakhjiri
- & Mahdi Ghadiri
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| Open AccessDeep eutectic solvents for antiepileptic drug phenytoin solubilization: thermodynamic study
- Hemayat Shekaari
- , Mohammed Taghi Zafarani-Moattar
- & Saeid Faraji
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| Open AccessPreparation of siRNA–PLGA/Fabʹ–PLGA mixed micellar system with target cell-specific recognition
- Mai Hazekawa
- , Takuya Nishinakagawa
- & Daisuke Ishibashi
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| Open AccessTargeting ROS/NF-κB signaling pathway by the seedless black Vitis vinifera polyphenols in CCl4-intoxicated kidney, lung, brain, and spleen in rats
- Noha H. Habashy
- , Ahmad S. Kodous
- & Marwa M. Abu-Serie
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| Open AccessMeta-regression of randomized control trials with antithrombotics: weak correlation between net clinical benefit and all cause-mortality
- Roubi Kilo
- , Silvy Laporte
- & Jean-Christophe Lega
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| Open AccessCVD 103-HgR live, attenuated cholera vaccine strain viability in drinking waters from the US and Europe
- R. Paul Duffin
- , Michael Delbuono
- & Amish A. Patel
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| Open AccessAnalytical quality by design methodology for botanical raw material analysis: a case study of flavonoids in Genkwa Flos
- Min Kyoung Kim
- , Sang Cheol Park
- & Young Pyo Jang
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| Open AccessIn vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIbα
- Benjamin Xiaoyi Li
- , Xiangrong Dai
- & Heyu Ni
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| Open AccessFreeze–thaw characterization process to minimize aggregation and enable drug product manufacturing of protein based therapeutics
- Keethkumar Jain
- , Nazila Salamat-Miller
- & Katherine Taylor
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Article
| Open AccessSmall molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers
- Martina Meßner
- , Melanie M. Mandl
- & Johanna Pachmayr
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| Open AccessA physicochemical assessment of the thermal stability of dextrin–colistin conjugates
- Emilie Chiron
- , Mathieu Varache
- & Elaine L. Ferguson
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Article
| Open AccessGliadin-mediated green preparation of hybrid zinc oxide nanospheres with antibacterial activity and low toxicity
- Qun Wang
- , Peng Ji
- & Jinyan Wu
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| Open AccessUse of omeprazole, the proton pump inhibitor, as a potential therapy for the capecitabine-induced hand-foot syndrome
- Shiori Hiromoto
- , Takehiro Kawashiri
- & Takao Shimazoe
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| Open AccessA cell based assay for evaluating binding and uptake of an antibody using hepatic nonparenchymal cells
- Yuki Noguchi
- , Kazuhisa Ozeki
- & Hidetaka Akita
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| Open AccessA dose-escalating toxicology study of the candidate biologic ELP-VEGF
- Jamarius P. Waller
- , Stephen P. Burke
- & Gene L. Bidwell III
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Article
| Open AccessConcomitant drugs associated with increased mortality for MDMA users reported in a drug safety surveillance database
- Isaac V. Cohen
- , Tigran Makunts
- & Kelan Thomas
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| Open AccessEnteric reabsorption processes and their impact on drug pharmacokinetics
- Manuel Ibarra
- , Iñaki F. Trocóniz
- & Pietro Fagiolino
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| Open AccessBeneficial effects of elafibranor on NASH in E3L.CETP mice and differences between mice and men
- Anita M. van den Hoek
- , Lars Verschuren
- & Hans M. G. Princen
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| Open AccessPreparation and application of a thidiazuron·diuron ultra-low-volume spray suitable for plant protection unmanned aerial vehicles
- Qin Liu
- , Kun Wei
- & Wei Xue
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| Open AccessDevelopment of water-soluble prodrugs of the bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity
- Hana Bavlovič Piskáčková
- , Hana Jansová
- & Petra Štěrbová-Kovaříková
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Article
| Open AccessDetermination of the composition of heterogeneous binder solutions by surface plasmon resonance biosensing
- Jimmy Gaudreault
- , Benoît Liberelle
- & Gregory De Crescenzo
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Article
| Open AccessbFGF and collagen matrix hydrogel attenuates burn wound inflammation through activation of ERK and TRK pathway
- Srijita Chakrabarti
- , Bhaskar Mazumder
- & Pronobesh Chattopadhyay
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| Open AccessPrediction of pharmacological activities from chemical structures with graph convolutional neural networks
- Miyuki Sakai
- , Kazuki Nagayasu
- & Shuji Kaneko
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| Open AccessDesign and development of innovative microparticulate/nanoparticulate inhalable dry powders of a novel synthetic trifluorinated chalcone derivative and Nrf2 agonist
- Priya Muralidharan
- , Brielle Jones
- & Heidi M. Mansour
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| Open AccessMeasuring dissolution profiles of single controlled-release drug pellets
- Heran C. Bhakta
- , Jessica M. Lin
- & William H. Grover
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| Open AccessPharmacokinetic–pharmacodynamic modelling of the hypoglycaemic effect of pulsatile administration of human insulin in rats
- Makoto Miyazaki
- , Mariko Hayata
- & Junya Nagai
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| Open AccessIn-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach
- Laura Mecozzi
- , Martina Mambrini
- & Fabio Franco Stellari
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| Open AccessDesign and in vivo evaluation of a microparticulate depot formulation of buprenorphine for veterinary use
- Viktoria Schreiner
- , Mattea Durst
- & Jörg Huwyler
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| Open AccessModeling the dynamics of antibody–target binding in living tumors
- Yu Tang
- & Yanguang Cao
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| Open AccessPharmacokinetic prediction of an antibody in mice based on an in vitro cell-based approach using target receptor-expressing cells
- Yuki Noguchi
- , Kazuhisa Ozeki
- & Hidetaka Akita
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Article
| Open AccessReproducible production and image-based quality evaluation of retinal pigment epithelium sheets from human induced pluripotent stem cells
- Ke Ye
- , Yuto Takemoto
- & Fumitaka Osakada
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| Open AccessEpigenetics meets GPCR: inhibition of histone H3 methyltransferase (G9a) and histamine H3 receptor for Prader–Willi Syndrome
- David Reiner
- , Ludwig Seifert
- & Holger Stark
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| Open AccessThe discovery of a new antibody for BRIL-fused GPCR structure determination
- Hikaru Miyagi
- , Hidetsugu Asada
- & Jun-ichi Saito
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| Open AccessGeneration of a canine anti-canine CD20 antibody for canine lymphoma treatment
- Takuya Mizuno
- , Yukinari Kato
- & Masaya Igase
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| Open AccessRobustaflavone induces G0/G1 cell cycle arrest and apoptosis in human umbilical vein endothelial cells and exhibits anti-angiogenic effects in vivo
- Woo Kyung Sim
- , Jong-Hwa Park
- & In Sik Chung
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| Open AccessPreparation of high drug-loading celastrol nanosuspensions and their anti-breast cancer activities in vitro and in vivo
- Tiantian Huang
- , Yian Wang
- & Xiangtao Wang
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| Open AccessEnhanced insulin receptor interaction by a bifunctional insulin-transferrin fusion protein: an approach to overcome insulin resistance
- Yuqian Liu
- , Hsuan-Yao Wang
- & Wei-Chiang Shen
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| Open AccessDietary countermeasure mitigates simulated spaceflight-induced osteopenia in mice
- Sonette Steczina
- , Candice G. T. Tahimic
- & Ann-Sofie Schreurs
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| Open AccessGeneration of intestinal organoids derived from human pluripotent stem cells for drug testing
- Shinpei Yoshida
- , Hiroto Miwa
- & Koji Takahashi
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| Open AccessThe cardiac work-loop technique: An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles
- Sophie Fletcher
- , Helen Maddock
- & Mayel Gharanei
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| Open AccessThe anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor
- Barbara Żyżyńska-Granica
- , Bartosz Trzaskowski
- & Katarzyna Koziak
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| Open AccessNanocatalytic activity of clean-surfaced, faceted nanocrystalline gold enhances remyelination in animal models of multiple sclerosis
- Andrew P. Robinson
- , Joanne Zhongyan Zhang
- & Stephen D. Miller