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| Open AccessModeling the role of endoplasmic reticulum-mitochondria microdomains in calcium dynamics
- Arash Moshkforoush
- , Baarbod Ashenagar
- & B. Rita Alevriadou
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| Open AccessHigh-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na+ channel complex
- Paul A. Wadsworth
- , Oluwarotimi Folorunso
- & Fernanda Laezza
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Article
| Open AccessA pore-occluding phenylalanine gate prevents ion slippage through plant ammonium transporters
- Pascal Ganz
- , Robin Mink
- & Benjamin Neuhäuser
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| Open AccessA family of orthologous proteins from centipede venoms inhibit the hKir6.2 channel
- Yajamana Ramu
- & Zhe Lu
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| Open AccessCompetitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP2 Suggest a Mechanism for Regulation
- Nicholas J. Sisco
- , Cole V. M. Helsell
- & Wade D. Van Horn
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| Open AccessShort-term consequences of F508del-CFTR thermal instability on CFTR-dependent transepithelial currents in human airway epithelial cells
- Lionel Froux
- , Christelle Coraux
- & Frédéric Becq
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| Open AccessMicroarray-based screening system identifies temperature-controlled activity of Connexin 26 that is distorted by mutations
- Hongling Wang
- , Frank Stahl
- & Carsten Zeilinger
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| Open AccessPhosphorylation-dependent modulation of CFTR macromolecular signalling complex activity by cigarette smoke condensate in airway epithelia
- Andrea Schnúr
- , Aiswarya Premchandar
- & Gergely L. Lukacs
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Article
| Open AccessMiltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms
- Sara Botschuijver
- , Sophie A. van Diest
- & René M. van den Wijngaard
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Article
| Open AccessBioactive Thymosin Alpha-1 Does Not Influence F508del-CFTR Maturation and Activity
- Andrea Armirotti
- , Valeria Tomati
- & Nicoletta Pedemonte
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Article
| Open AccessEvidence for potassium transport activity of Arabidopsis KEA1-KEA6
- Masaru Tsujii
- , Kota Kera
- & Nobuyuki Uozumi
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Article
| Open AccessThe molecular nature of the 17β-Estradiol binding site in the voltage- and Ca2+-activated K+ (BK) channel β1 subunit
- Sara T. Granados
- , Karen Castillo
- & Yolima P. Torres
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Article
| Open AccessA novel motif in the proximal C-terminus of Pannexin 1 regulates cell surface localization
- Anna L. Epp
- , Sarah N. Ebert
- & Leigh Anne Swayne
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Article
| Open AccessUridine as a protector against hypoxia-induced lung injury
- Ekaterina V. Rozova
- , Irina N. Mankovskaya
- & Galina D. Mironova
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Article
| Open AccessK+ and Cl− channels/transporters independently fine-tune photosynthesis in plants
- Emilija Dukic
- , Andrei Herdean
- & Cornelia Spetea
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Article
| Open AccessOsmotic tolerance of avian erythrocytes to complete hemolysis in solute free water
- Snigdha Singh
- , Nisha Ponnappan
- & Aditya Mittal
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Article
| Open AccessThe structural arrangement at intersubunit interfaces in homomeric kainate receptors
- Douglas B. Litwin
- , Elisa Carrillo
- & Vasanthi Jayaraman
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Article
| Open AccessFunctional Analysis of Conserved Transmembrane Charged Residues and a Yeast Specific Extracellular Loop of the Plasma Membrane Na+/H+ Antiporter of Schizosaccharomyces pombe
- Debajyoti Dutta
- , Asad Ullah
- & Larry Fliegel
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Article
| Open AccessResidues 529 to 549 participate in membrane penetration and pore-forming activity of the Bordetella adenylate cyclase toxin
- Jana Roderova
- , Adriana Osickova
- & Jiri Masin
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Article
| Open AccessRNA interference-mediated knockdown of voltage-gated sodium channel (MpNav) gene causes mortality in peach-potato aphid, Myzus persicae
- Kaleem Tariq
- , Asad Ali
- & Farman Ullah
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Article
| Open AccessTRPM2 ion channel promotes gastric cancer migration, invasion and tumor growth through the AKT signaling pathway
- Shekoufeh Almasi
- , Andra M. Sterea
- & Yassine El Hiani
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Article
| Open AccessG protein-coupled and ATP-sensitive inwardly rectifying potassium ion channels are essential for HIV entry
- Ravi C. Dubey
- , Nawneet Mishra
- & Ritu Gaur
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Article
| Open AccessMutations in the palm domain disrupt modulation of acid-sensing ion channel 1a currents by neuropeptides
- Benoîte Bargeton
- , Justyna Iwaszkiewicz
- & Stephan Kellenberger
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Article
| Open AccessMutual action by Gγ and Gβ for optimal activation of GIRK channels in a channel subunit-specific manner
- Galit Tabak
- , Tal Keren-Raifman
- & Nathan Dascal
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Article
| Open AccessStandardized phytotherapic extracts rescue anomalous locomotion and electrophysiological responses of TDP-43 Drosophila melanogaster model of ALS
- Riccardo Maccioni
- , Maria Dolores Setzu
- & Anna Liscia
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Article
| Open AccessRelative positioning of Kv11.1 (hERG) K+ channel cytoplasmic domain-located fluorescent tags toward the plasma membrane
- Francisco Barros
- , Pedro Domínguez
- & Pilar de la Peña
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Article
| Open AccessParkin-dependent regulation of the MCU complex component MICU1
- Alessandra Matteucci
- , Maria Patron
- & Tito Calì
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Article
| Open AccessBlocking ion channels induced by antifungal lipopeptide syringomycin E with amide-linked local anesthetics
- Anastasiia A. Zakharova
- , Svetlana S. Efimova
- & Olga S. Ostroumova
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Article
| Open AccessHuman erythrocytes release ATP by a novel pathway involving VDAC oligomerization independent of pannexin-1
- Irene Marginedas-Freixa
- , Cora Lilia Alvarez
- & Mariano Anibal Ostuni
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Article
| Open AccessSite-specific ion occupation in the selectivity filter causes voltage-dependent gating in a viral K+ channel
- O. Rauh
- , U. P. Hansen
- & I. Schroeder
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Article
| Open AccessHypokalaemic periodic paralysis and myotonia in a patient with homozygous mutation p.R1451L in NaV1.4
- Sushan Luo
- , Marisol Sampedro Castañeda
- & Roope Männikkö
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Article
| Open AccessThe C-terminal HRET sequence of Kv1.3 regulates gating rather than targeting of Kv1.3 to the plasma membrane
- Orsolya Voros
- , Orsolya Szilagyi
- & Péter Hajdu
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Article
| Open AccessIon Permeation Mechanism in Epithelial Calcium Channel TRVP6
- Serzhan Sakipov
- , Alexander I. Sobolevsky
- & Maria G. Kurnikova
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Article
| Open AccessOrthogonality of Pyrrolysine tRNA in the Xenopus oocyte
- Daniel T. Infield
- , John D. Lueck
- & Christopher A. Ahern
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Article
| Open AccessSolution structure of extracellular loop of human β4 subunit of BK channel and its biological implication on ChTX sensitivity
- Yanting Wang
- , Wenxian Lan
- & Chunyang Cao
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Article
| Open AccessThe voltage-gated sodium channel EF-hands form an interaction with the III-IV linker that is disturbed by disease-causing mutations
- Bernd R. Gardill
- , Ricardo E. Rivera-Acevedo
- & Filip Van Petegem
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Article
| Open AccessAn allosteric link connecting the lipid-protein interface to the gating of the nicotinic acetylcholine receptor
- Jaimee A. Domville
- & John E. Baenziger
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Article
| Open AccessTRPV4-mediates oscillatory fluid shear mechanotransduction in mesenchymal stem cells in part via the primary cilium
- Michele A. Corrigan
- , Gillian P. Johnson
- & David A. Hoey
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Article
| Open AccessFunctional analysis of SLC39A8 mutations and their implications for manganese deficiency and mitochondrial disorders
- Eun-Kyung Choi
- , Trang-Tiffany Nguyen
- & Young Ah Seo
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Article
| Open AccessPolygonum aviculare L. extract and quercetin attenuate contraction in airway smooth muscle
- Xi Luo
- , Lu Xue
- & Qing-Hua Liu
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| Open AccessInactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry
- Pavani Beesetty
- , Krystyna B. Wieczerzak
- & J. Ashot Kozak
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Article
| Open AccessATP12A promotes mucus dysfunction during Type 2 airway inflammation
- Alison T. Lennox
- , Stefanie L. Coburn
- & Mike M. Myerburg
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Article
| Open AccessPhysical basis of specificity and delayed binding of a subtype selective sodium channel inhibitor
- Ben Corry
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Article
| Open AccessProbing the molecular basis of hERG drug block with unnatural amino acids
- Logan C. Macdonald
- , Robin Y. Kim
- & David Fedida
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Article
| Open AccessStructural insights into the potency of SK channel positive modulators
- Young-Woo Nam
- , Razan Orfali
- & Miao Zhang
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| Open AccessNa+ entry through heteromeric TRPC4/C1 channels mediates (−)Englerin A-induced cytotoxicity in synovial sarcoma cells
- Katsuhiko Muraki
- , Kaori Ohnishi
- & David J. Beech
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Article
| Open AccessInteraction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors
- Thomas Durek
- , Irina V. Shelukhina
- & Victor I. Tsetlin
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Article
| Open AccessMolecular architecture of potassium chloride co-transporter KCC2
- Morgane Agez
- , Patrick Schultz
- & Anass Jawhari
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Article
| Open AccessThe E. coli dicarboxylic acid transporters DauA act as a signal transducer by interacting with the DctA uptake system
- Eleni Karinou
- , Paul A. Hoskisson
- & Arnaud Javelle