Featured
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Article
| Open AccessMolecular and cellular correlates in Kv channel clustering: entropy-based regulation of cluster ion channel density
- Limor Lewin
- , Esraa Nsasra
- & Ofer Yifrach
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Article
| Open AccessBeyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities
- Johara Boldrini-França
- , Ernesto Lopes Pinheiro-Junior
- & Jan Tytgat
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Article
| Open AccessStructure-activity relationship studies of four novel 4-aminopyridine K+ channel blockers
- Sofia Rodríguez-Rangel
- , Alyssa D. Bravin
- & Jorge E. Sánchez-Rodríguez
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Article
| Open AccessA family of orthologous proteins from centipede venoms inhibit the hKir6.2 channel
- Yajamana Ramu
- & Zhe Lu
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Article
| Open AccessEvidence for potassium transport activity of Arabidopsis KEA1-KEA6
- Masaru Tsujii
- , Kota Kera
- & Nobuyuki Uozumi
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Article
| Open AccessThe molecular nature of the 17β-Estradiol binding site in the voltage- and Ca2+-activated K+ (BK) channel β1 subunit
- Sara T. Granados
- , Karen Castillo
- & Yolima P. Torres
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Article
| Open AccessUridine as a protector against hypoxia-induced lung injury
- Ekaterina V. Rozova
- , Irina N. Mankovskaya
- & Galina D. Mironova
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Article
| Open AccessG protein-coupled and ATP-sensitive inwardly rectifying potassium ion channels are essential for HIV entry
- Ravi C. Dubey
- , Nawneet Mishra
- & Ritu Gaur
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Article
| Open AccessMutual action by Gγ and Gβ for optimal activation of GIRK channels in a channel subunit-specific manner
- Galit Tabak
- , Tal Keren-Raifman
- & Nathan Dascal
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Article
| Open AccessStandardized phytotherapic extracts rescue anomalous locomotion and electrophysiological responses of TDP-43 Drosophila melanogaster model of ALS
- Riccardo Maccioni
- , Maria Dolores Setzu
- & Anna Liscia
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Article
| Open AccessRelative positioning of Kv11.1 (hERG) K+ channel cytoplasmic domain-located fluorescent tags toward the plasma membrane
- Francisco Barros
- , Pedro Domínguez
- & Pilar de la Peña
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Article
| Open AccessSite-specific ion occupation in the selectivity filter causes voltage-dependent gating in a viral K+ channel
- O. Rauh
- , U. P. Hansen
- & I. Schroeder
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Article
| Open AccessThe C-terminal HRET sequence of Kv1.3 regulates gating rather than targeting of Kv1.3 to the plasma membrane
- Orsolya Voros
- , Orsolya Szilagyi
- & Péter Hajdu
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Article
| Open AccessSolution structure of extracellular loop of human β4 subunit of BK channel and its biological implication on ChTX sensitivity
- Yanting Wang
- , Wenxian Lan
- & Chunyang Cao
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Article
| Open AccessProbing the molecular basis of hERG drug block with unnatural amino acids
- Logan C. Macdonald
- , Robin Y. Kim
- & David Fedida
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Article
| Open AccessMolecular architecture of potassium chloride co-transporter KCC2
- Morgane Agez
- , Patrick Schultz
- & Anass Jawhari
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Article
| Open AccessCalmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels
- Alessandro Alaimo
- , Eider Nuñez
- & Alvaro Villarroel
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Article
| Open AccessATP-sensitive inwardly rectifying potassium channel regulation of viral infections in honey bees
- Scott T. O’Neal
- , Daniel R. Swale
- & Troy D. Anderson
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Article
| Open AccessKv3.4 is modulated by HIF-1α to protect SH-SY5Y cells against oxidative stress-induced neural cell death
- Min Seok Song
- , Pan Dong Ryu
- & So Yeong Lee
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Article
| Open AccessRestoration of the growth of Escherichia coli under K+-deficient conditions by Cs+ incorporation via the K+ transporter Kup
- Souichiro Kato
- , Yoshiki Kanata
- & Yoichi Kamagata
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Article
| Open AccessTbIRK is a signature sequence free potassium channel from Trypanosoma brucei locating to acidocalcisomes
- Michael E. Steinmann
- , Remo S. Schmidt
- & Erwin Sigel
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Article
| Open AccessRecombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels
- Nicole Bobak
- , Sylvain Feliciangeli
- & Florian Lesage
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Article
| Open AccessPhosphatidylinositol (4,5)-bisphosphate dynamically regulates the K2P background K+ channel TASK-2
- María Isabel Niemeyer
- , L. Pablo Cid
- & Francisco V. Sepúlveda
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Article
| Open AccessRemote control of glucose homeostasis in vivo using photopharmacology
- Zenobia B. Mehta
- , Natalie R. Johnston
- & David J. Hodson
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Article
| Open AccessTuning the allosteric regulation of artificial muscarinic and dopaminergic ligand-gated potassium channels by protein engineering of G protein-coupled receptors
- Christophe J. Moreau
- , Jean Revilloud
- & Michel Vivaudou
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Article
| Open AccessCullin 7 mediates proteasomal and lysosomal degradations of rat Eag1 potassium channels
- Po-Hao Hsu
- , Yu-Ting Ma
- & Chung-Jiuan Jeng
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Article
| Open AccessDisulfide mapping the voltage-sensing mechanism of a voltage-dependent potassium channel
- Tomohiro Nozaki
- , Shin-ichiro Ozawa
- & Ichio Shimada
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Article
| Open AccessFunctional kinomics establishes a critical node of volume-sensitive cation-Cl− cotransporter regulation in the mammalian brain
- Jinwei Zhang
- , Geng Gao
- & Kristopher T. Kahle
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Article
| Open AccessThe antifungal plant defensin AtPDF2.3 from Arabidopsis thaliana blocks potassium channels
- Kim Vriens
- , Steve Peigneur
- & Karin Thevissen
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Article
| Open AccessFly DPP10 acts as a channel ancillary subunit and possesses peptidase activity
- Yohei Shiina
- , Tomohiro Muto
- & Koichi Takimoto
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Article
| Open AccessAn engineered scorpion toxin analogue with improved Kv1.3 selectivity displays reduced conformational flexibility
- Adam Bartok
- , Krisztina Fehér
- & Zoltan Varga
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Article
| Open AccessAlkanols inhibit voltage-gated K+ channels via a distinct gating modifying mechanism that prevents gate opening
- Evelyn Martínez-Morales
- , Ivan Kopljar
- & Alain J. Labro
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Article
| Open AccessModular Design of the Selectivity Filter Pore Loop in a Novel Family of Prokaryotic ‘Inward Rectifier’ (NirBac) channels
- Lejla Zubcevic
- , Shizhen Wang
- & Stephen J. Tucker
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Article
| Open AccessStructural basis for the inhibition of voltage-dependent K+ channel by gating modifier toxin
- Shin-ichiro Ozawa
- , Tomomi Kimura
- & Masanori Osawa
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Article
| Open AccessA distinct three-helix centipede toxin SSD609 inhibits Iks channels by interacting with the KCNE1 auxiliary subunit
- Peibei Sun
- , Fangming Wu
- & Changlin Tian
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Article
| Open AccessAuxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels
- Jens-Peter David
- , Jeroen I. Stas
- & Elke Bocksteins
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Article
| Open AccessToxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel
- Zongyun Chen
- , Youtian Hu
- & Yingliang Wu
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Article
| Open AccessPIP2-dependent coupling is prominent in Kv7.1 due to weakened interactions between S4-S5 and S6
- Marina A. Kasimova
- , Mark A. Zaydman
- & Mounir Tarek
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Article
| Open AccessLabel-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel
- Haiyan Sun
- , Ying Wei
- & Ye Fang
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Article
| Open AccessA functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris
- Mandeep S. Dhillon
- , Christopher J. Cockcroft
- & Asipu Sivaprasadarao
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Article
| Open AccessThe Large Conductance, Calcium-activated K+ (BK) Channel is regulated by Cysteine String Protein
- Barry D. Kyle
- , Eva Ahrendt
- & Janice E. A. Braun
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| Open AccessFunction of Shaker potassium channels produced by cell-free translation upon injection into Xenopus oocytes
- Brian W. Jarecki
- , Shin-ichi Makino
- & Baron Chanda