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| Open AccessAiKPro: deep learning model for kinome-wide bioactivity profiling using structure-based sequence alignments and molecular 3D conformer ensemble descriptors
- Hyejin Park
- , Sujeong Hong
- & Jae-Min Shin
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| Open AccessInvestigation of enzalutamide, docetaxel, and cabazitaxel resistance in the castration resistant prostate cancer cell line C4 using genome-wide CRISPR/Cas9 screening
- Jakob Haldrup
- , Simone Weiss
- & Karina Dalsgaard Sørensen
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| Open AccessOptimized metrics for orthogonal combinatorial CRISPR screens
- Ronay Cetin
- , Martin Wegner
- & Manuel Kaulich
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| Open AccessMasitinibL shows promise as a drug-like analog of masitinib that elicits comparable SARS-Cov-2 3CLpro inhibition with low kinase preference
- Olanrewaju Ayodeji Durojaye
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- & Bennett Chima Nwanguma
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| Open AccessA prospective study on linking diarrheagenic E. coli with stunted childhood growth in relation to gut microbiome
- Israr Aziz
- , Zobia Noreen
- & Habib Bokhari
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| Open AccessImproving the efficiency of aerosolized insecticide testing against mosquitoes
- Walter Fabricio Silva Martins
- , Emma Reid
- & David Weetman
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| Open AccessThe systematic comparison between Gaussian mirror and Model-X knockoff models
- Shuai Chen
- , Ziqi Li
- & Yalu Wen
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| Open AccessPatients with ACPA-positive and ACPA-negative rheumatoid arthritis show different serological autoantibody repertoires and autoantibody associations with disease activity
- Kevin Y. Cunningham
- , Benjamin Hur
- & Jaeyun Sung
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| Open AccessAn ultra-high-throughput screen for the evaluation of peptide HLA-Binder interactions
- Stefan Krämer
- , Andreas Moritz
- & Johannes Wöhrle
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| Open AccessDiscovery of novel cardiac troponin activators using fluorescence polarization-based high throughput screening assays
- Priyanka Parijat
- , Saraswathi Ponnam
- & Thomas Kampourakis
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| Open AccessNon-destructive high-throughput measurement of elastic-viscous properties of maize using a novel ultra-micro sensor array and numerical validation
- Taiken Nakashima
- , Haruka Tomobe
- & Hitoshi Morikawa
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| Open AccessOptimization of a high-throughput nanofluidic real-time PCR to detect and quantify of 15 bacterial species and 92 Streptococcus pneumoniae serotypes
- Sarah L. Downs
- , Shabir. A. Madhi
- & Courtney P. Olwagen
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| Open AccessA high throughput method for egg size measurement in Drosophila
- Neda Barghi
- & Claudia Ramirez-Lanzas
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| Open AccessHigh-throughput isolation of cancer cells in spiral microchannel by changing the direction, magnitude and location of the maximum velocity
- Vahid Omrani
- , Mohammad Zabetian Targhi
- & Reza Nosrati
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| Open AccessHigher throughput workflow with sensitive, reliable and automatic quantification of myelination in vitro suitable for drug screening
- Sybille Seiler
- , Ciril Marius Wälti
- & Lynette C. Foo
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| Open AccessMagnetic hydrogel particles improve nanopore sequencing of SARS-CoV-2 and other respiratory viruses
- P. Andersen
- , S. Barksdale
- & B. Lepene
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| Open AccessIdentification of essential genes and immune cell infiltration in rheumatoid arthritis by bioinformatics analysis
- You Ao
- , Zhongbo Wang
- & Wei Zhang
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| Open AccessAnalyses of binding partners and functional domains for the developmentally essential protein Hmx3a/HMX3
- William Haws
- , Samantha England
- & Katharine Lewis
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| Open AccessIonomics-metabolome association analysis as a new approach to the impact of dietary copper levels in suckling piglets model
- Feng Zhang
- , Wen Yao
- & Erhui Jin
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| Open AccessEvaluation of automated techniques for extraction of circulating cell-free DNA for implementation in standardized high-throughput workflows
- Sarah Lehle
- , Julius Emons
- & Hanna Huebner
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| Open AccessDirect detection of circulating donor-derived extracellular vesicles in kidney transplant recipients
- Wouter W. Woud
- , Dennis A. Hesselink
- & Karin Boer
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| Open AccessDysregulated thrombospondin 1 and miRNA-29a-3p in severe COVID-19
- In Soo Kim
- , Sung-Gwon Lee
- & Chungoo Park
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| Open AccessHigh-throughput primer design by scoring in piecewise logistic model for multiple polymerase chain reaction variants
- Huaping Zeng
- , Kexin Chen
- & Yu Wang
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| Open AccessCheminformatics analysis of chemicals that increase estrogen and progesterone synthesis for a breast cancer hazard assessment
- Alexandre Borrel
- & Ruthann A. Rudel
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| Open AccessA genotyping by sequencing approach can disclose Apis mellifera population genomic information contained in honey environmental DNA
- Samuele Bovo
- , Valerio Joe Utzeri
- & Luca Fontanesi
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| Open AccessA robust bacterial high-throughput screening system to evaluate single nucleotide polymorphisms of human homogentisate 1,2-dioxygenase in the context of alkaptonuria
- Sien Lequeue
- , Jessie Neuckermans
- & Joery De Kock
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| Open AccessGeneration of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2
- Carola Gregor
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| Open AccessThe effect of mutations on binding interactions between the SARS-CoV-2 receptor binding domain and neutralizing antibodies B38 and CB6
- Jonathan E. Barnes
- , Peik K. Lund-Andersen
- & F. Marty Ytreberg
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| Open AccessParallel functional annotation of cancer-associated missense mutations in histone methyltransferases
- Ashley J. Canning
- , Susan Viggiano
- & Michael S. Cosgrove
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| Open AccessDiscovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells
- Xammy Nguyenla
- , Eddie Wehri
- & Julia Schaletzky
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| Open AccessA novel metagenome-derived viral RNA polymerase and its application in a cell-free expression system for metagenome screening
- Yuchen Han
- , Birhanu M. Kinfu
- & Wolfgang R. Streit
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| Open AccessMetagenomic analysis of viromes in tissues of wild Qinghai vole from the eastern Tibetan Plateau
- Xiaozhou He
- , Xu Wang
- & Xuejun Ma
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| Open AccessExperimental considerations of acute heat stress assays to quantify coral thermal tolerance
- J. J. V. Nielsen
- , G. Matthews
- & L. K. Bay
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| Open AccessForward genetic screening identifies novel roles for N-terminal acetyltransferase C and histone deacetylase in C. elegans development
- Rose Aria Malinow
- , Ming Zhu
- & Kyung Won Kim
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| Open AccessClinical and NGS predictors of response to regorafenib in recurrent glioblastoma
- Silvia Chiesa
- , Antonella Mangraviti
- & Quintino Giorgio D’Alessandris
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| Open AccessAutomated in vivo compound screening with zebrafish and the discovery and validation of PD 81,723 as a novel angiogenesis inhibitor
- Antonio N. Mauro
- , Paul J. Turgeon
- & Krishna K. Singh
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| Open AccessLarge scale screening of CRISPR guide RNAs using an optimized high throughput robotics system
- J. R. Spangler
- , T. A. Leski
- & D. A. Stenger
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| Open AccessApplication of immune enhanced organoids in modeling personalized Merkel cell carcinoma research
- Steven D. Forsythe
- , Richard A. Erali
- & Konstantinos I. Votanopoulos
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| Open AccessDevelopment of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells
- Oxana V. Denisova
- , Joni Merisaari
- & Jukka Westermarck
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| Open AccessIdentification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus
- Deepika Chaudhary
- , Avantika Singh
- & Ramandeep Singh
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| Open AccessEvaluation of rapid transepithelial electrical resistance (TEER) measurement as a metric of kidney toxicity in a high-throughput microfluidic culture system
- Erin M. Shaughnessey
- , Samuel H. Kann
- & Else M. Vedula
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| Open AccessPollen derived macromolecules serve as a new class of ice-nucleating cryoprotectants
- Kathryn A. Murray
- , Nina L. H. Kinney
- & Thomas F. Whale
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| Open AccessTemporal response characterization across individual multiomics profiles of prediabetic and diabetic subjects
- Minzhang Zheng
- , Carlo Piermarocchi
- & George I. Mias
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| Open AccessDNA methylation fingerprint of hepatocellular carcinoma from tissue and liquid biopsies
- Emanuel Gonçalves
- , Maria Gonçalves-Reis
- & Joana Cardoso
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| Open AccessShifts in rhizosphere microbial communities in Oplopanax elatus Nakai are related to soil chemical properties under different growth conditions
- Wanying Li
- , Xiujuan Lei
- & Yingping Wang
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| Open AccessApplication of multiplex amplicon deep-sequencing (MAD-seq) to screen for putative drug resistance markers in the Necator americanus isotype-1 β-tubulin gene
- Santosh George
- , Peter Suwondo
- & Michael Cappello
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| Open AccessWhole-body transcriptome analysis provides insights into the cascade of sequential expression events involved in growth, immunity, and metabolism during the molting cycle in Scylla paramamosain
- Lei Liu
- , Xiao Liu
- & Chunlin Wang
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| Open AccessCRISPR/Cas9-based genome-wide screening of Dictyostelium
- Takanori Ogasawara
- , Jun Watanabe
- & Tetsuya Muramoto
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| Open AccessMicroliter-scale reaction arrays for economical high-throughput experimentation in radiochemistry
- Alejandra Rios
- , Travis S. Holloway
- & R. Michael van Dam