Endoplasmic reticulum articles within Scientific Reports

Featured

• Article
  21 September 2023 | Open Access

  Characterization of signal and transit peptides based on motif composition and taxon-specific patterns

  • Katarzyna Sidorczuk
  • , Paweł Mackiewicz
  •  & Przemysław Gagat

• Article
  06 September 2023 | Open Access

  Structural and functional analysis of aquaporin-2 mutants involved in nephrogenic diabetes insipidus

  • Carl Johan Hagströmer
  • , Jonas Hyld Steffen
  •  & Susanna Törnroth-Horsefield

• Article
  31 August 2023 | Open Access

  Biochemical analysis of Komagataella phaffii oxidative folding proposes novel regulatory mechanisms of disulfide bond formation in yeast

  • Arianna Palma
  • , Lukas A. Rettenbacher
  •  & Lloyd Ruddock

• Article
  09 March 2023 | Open Access

  CRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neuronal cell death

  • Sofia Pavlou
  • , Stefanie Foskolou
  •  & Emmanouil Metzakopian

• Article
  25 July 2022 | Open Access

  Empagliflozin mitigates endothelial inflammation and attenuates endoplasmic reticulum stress signaling caused by sustained glycocalyx disruption

  • Marc-Antoine Campeau
  •  & Richard L. Leask

• Article
  13 July 2022 | Open Access

  Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability

  • Takumi Taketomi
  • , Takunori Yasuda
  •  & Fuminori Tsuruta

• Article
  24 May 2022 | Open Access

  Development of a stable antibody production system utilizing an Hspa5 promoter in CHO cells

  • Hiroki Tanemura
  • , Kenji Masuda
  •  & Ryo Ushioda

• Article
  21 March 2022 | Open Access

  Thioredoxin interacting protein protects mice from fasting induced liver steatosis by activating ER stress and its downstream signaling pathways

  • Hiroyuki Miyahara
  • , Kosei Hasegawa
  •  & Hirokazu Tsukahara

• Article
  02 November 2021 | Open Access

  Ca²⁺ imbalance caused by ERdj5 deletion affects mitochondrial fragmentation

  • Riyuji Yamashita
  • , Shohei Fujii
  •  & Kazuhiro Nagata

• Article
  26 October 2021 | Open Access

  Murine SEC24D can substitute functionally for SEC24C during embryonic development

  • Elizabeth J. Adams
  • , Rami Khoriaty
  •  & David Ginsburg

• Article
  16 September 2021 | Open Access

  Control of membrane protein homeostasis by a chaperone-like glial cell adhesion molecule at multiple subcellular locations

  • Haijin Xu
  • , Sandra Isenmann
  •  & Pirjo M. Apaja

• Article
  02 June 2021 | Open Access

  Ipomoeassin-F disrupts multiple aspects of secretory protein biogenesis

  • Peristera Roboti
  • , Sarah O’Keefe
  •  & Stephen High

• Article
  21 April 2021 | Open Access

  Alternative redox forms of ASNA-1 separate insulin signaling from tail-anchored protein targeting and cisplatin resistance in C. elegans

  • Dorota Raj
  • , Ola Billing
  •  & Peter Naredi

• Article
  04 February 2021 | Open Access

  Clinically-identified C-terminal mutations in fibulin-3 are prone to misfolding and destabilization

  • DaNae R. Woodard
  • , Emi Nakahara
  •  & John D. Hulleman

• Article
  01 December 2020 | Open Access

  Super resolution microscopy and deep learning identify Zika virus reorganization of the endoplasmic reticulum

  • Rory K. M. Long
  • , Kathleen P. Moriarty
  •  & Ivan R. Nabi

• Article
  25 November 2020 | Open Access

  Synaptic activity and strength are reflected by changes in the post-synaptic secretory pathway

  • Clara-Marie Gürth
  • , Tal M. Dankovich
  •  & Elisa D’Este

• Article
  28 July 2020 | Open Access

  Cigarette smoke induces endoplasmic reticulum stress and suppresses efferocytosis through the activation of RhoA

  • Hiroyuki Ito
  • , Yoshiro Yamashita
  •  & Konosuke Morimoto

• Article
  09 July 2020 | Open Access

  Genome-wide identification and characterization of Solanum tuberosum BiP genes reveal the role of the promoter architecture in BiP gene diversity

  • Venura Herath
  • , Mathieu Gayral
  •  & Jeanmarie Verchot

• Article
  23 June 2020 | Open Access

  High expression of spliced X-Box Binding Protein 1 in lung tumors is associated with cancer aggressiveness and epithelial-to-mesenchymal transition

  • Quentin Tavernier
  • , Antoine Legras
  •  & Nicolas Pallet

• Article
  06 May 2020 | Open Access

  Proteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation

  • Tomoyuki Yamanaka
  • , Risa Nishiyama
  •  & Nobuyuki Nukina

• Article
  06 March 2020 | Open Access

  Selective Binding of HSC70 and its Co-Chaperones to Structural Hotspots on CFTR

  • Imad Baaklini
  • , Conrado de Campos Gonçalves
  •  & Jason C. Young

• Article
  10 February 2020 | Open Access

  Endoplasmic reticulum stress promotes inflammation-mediated proteolytic activity at the ocular surface

  • Ashley M. Woodward
  • , Antonio Di Zazzo
  •  & Pablo Argüeso

• Article
  27 January 2020 | Open Access

  Endomembrane Protein Trafficking Regulated by a TvCyP2 Cyclophilin in the Protozoan Parasite, Trichomonas vaginalis

  • Hong-Ming Hsu
  • , Yu-Hsin Huang
  •  & Jung-Hsiang Tai

• Article
  16 January 2020 | Open Access

  The novel missense mutation Met48Lys in FKBP22 changes its structure and functions

  • Yoshihiro Ishikawa
  • , Nobuyo Mizuno
  •  & Hans Peter Bächinger

• Article
  13 December 2019 | Open Access

  Expression of XBP1s in peritoneal mesothelial cells is critical for inflammation-induced peritoneal fibrosis

  • An Liu
  • , Qiong Song
  •  & Meilan Zhou

• Article
  22 November 2019 | Open Access

  Lowering the culture temperature corrects collagen abnormalities caused by HSP47 gene knockout

  • Kazunori K. Fujii
  • , Yuki Taga
  •  & Takaki Koide

• Article
  11 September 2019 | Open Access

  CAND1 regulates lunapark for the proper tubular network of the endoplasmic reticulum

  • Hiroaki Kajiho
  • , Yasunori Yamamoto
  •  & Toshiaki Sakisaka

• Article
  28 August 2019 | Open Access

  A novel, dynein-independent mechanism focuses the endoplasmic reticulum around spindle poles in dividing Drosophila spermatocytes

  • Darya Karabasheva
  •  & Jeremy T. Smyth

• Article
  04 July 2019 | Open Access

  Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

  • Nicholas J. Barrows
  • , Yesseinia Anglero-Rodriguez
  •  & Mariano A. Garcia-Blanco

• Article
  14 June 2019 | Open Access

  Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins

  • Peter Shyu Jr.
  • , Benjamin S. H. Ng
  •  & Guillaume Thibault

• Article
  16 May 2019 | Open Access

  A combined in silico and in vitro study on mouse Serpina1a antitrypsin-deficiency mutants

  • Reto Eggenschwiler
  • , Atanas Patronov
  •  & Tobias Cantz

• Article
  14 May 2019 | Open Access

  COPII proteins exhibit distinct subdomains within each ER exit site for executing their functions

  • Miharu Maeda
  • , Kazuo Kurokawa
  •  & Kota Saito

• Article
  29 April 2019 | Open Access

  Tropomyosin-receptor kinase fused gene (TFG) regulates lipid production in human sebocytes

  • So-Ra Choi
  • , Yul-Lye Hwang
  •  & Chang Deok Kim

• Article
  13 March 2019 | Open Access

  Widespread PERK-dependent repression of ER targets in response to ER stress

  • Nir Gonen
  • , Niv Sabath
  •  & Reut Shalgi

• Article
  08 March 2019 | Open Access

  E-syt1 Re-arranges STIM1 Clusters to Stabilize Ring-shaped ER-PM Contact Sites and Accelerate Ca²⁺ Store Replenishment

  • Fei Kang
  • , Mengxuan Zhou
  •  & Liangyi Chen

• Article
  07 March 2019 | Open Access

  Local resources of polyribosomes and SER promote synapse enlargement and spine clustering after long-term potentiation in adult rat hippocampus

  • Michael A. Chirillo
  • , Mikayla S. Waters
  •  & Kristen M. Harris

• Article
  07 February 2019 | Open Access

  Unconventional secretion factor GRASP55 is increased by pharmacological unfolded protein response inducers in neurons

  • Anna Maria van Ziel
  • , Pablo Largo-Barrientos
  •  & Wiep Scheper

• Article
  23 January 2019 | Open Access

  PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress

  • Isabelle C. Romine
  •  & R. Luke Wiseman

• Article
  10 December 2018 | Open Access

  Bioluminescent reporter assay for monitoring ER stress in human beta cells

  • Maria J. L. Kracht
  • , Eelco J. P. de Koning
  •  & Arnaud Zaldumbide

• Article
  26 November 2018 | Open Access

  Usp9X Regulates Cell Death in Malignant Peripheral Nerve Sheath Tumors

  • E. Bianchetti
  • , S. J. Bates
  •  & K. A. Roth

• Article
  12 November 2018 | Open Access

  Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor

  • Jody Groenendyk
  • , Tautvydas Paskevicius
  •  & Marek Michalak

• Article
  06 November 2018 | Open Access

  PIWI proteins contribute to apoptosis during the UPR in human airway epithelial cells

  • Magdalena Gebert
  • , Sylwia Bartoszewska
  •  & Rafal Bartoszewski

• Article
  25 October 2018 | Open Access

  Ptf1a inactivation in adult pancreatic acinar cells causes apoptosis through activation of the endoplasmic reticulum stress pathway

  • Morito Sakikubo
  • , Kenichiro Furuyama
  •  & Yoshiya Kawaguchi

• Article
  10 August 2018 | Open Access

  A superfolder variant of pH-sensitive pHluorin for in vivo pH measurements in the endoplasmic reticulum

  • Mara Reifenrath
  •  & Eckhard Boles

• Article
  25 July 2018 | Open Access

  Spatially restricted subcellular Ca²⁺ signaling downstream of store-operated calcium entry encoded by a cortical tunneling mechanism

  • Raphael Courjaret
  • , Maya Dib
  •  & Khaled Machaca

• Article
  11 June 2018 | Open Access

  The intrinsically disordered E-domains regulate the IGF-1 prohormones stability, subcellular localisation and secretion

  • Giosuè Annibalini
  • , Serena Contarelli
  •  & Elena Barbieri

• Article
  27 March 2018 | Open Access

  Inhalational Anesthetics Induce Neuronal Protein Aggregation and Affect ER Trafficking

  • Matthew Coghlan
  • , Elizabeth Richards
  •  & Jason T. Maynes

• Article
  21 March 2018 | Open Access

  The transcriptional profiles and functional implications of long non-coding RNAs in the unfolded protein response

  • Hongyang Quan
  • , Qianqian Fan
  •  & Lin Wang

• Article
  02 March 2018 | Open Access

  Metabolic Reprogramming in Amyotrophic Lateral Sclerosis

  • M. Szelechowski
  • , N. Amoedo
  •  & R. Rossignol

• Article
  16 February 2018 | Open Access

  Role of intestinal trefoil factor in protecting intestinal epithelial cells from burn-induced injury

  • Jianhong Hu
  • , Yan Shi
  •  & Xi Peng