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| Open AccessThe ClC-3 chloride channel associated with microtubules is a target of paclitaxel in its induced-apoptosis
- Haifeng Zhang
- , Huarong Li
- & Lixin Chen
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| Open AccessThe flavonoid apigenin improves glucose tolerance through inhibition of microRNA maturation in miRNA103 transgenic mice
- Motoko Ohno
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- & Kazuhiko Koike
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| Open AccessSmall molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent
- Amaravadhi Harikishore
- , Makhtar Niang
- & Ho Sup Yoon
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| Open AccessInduction of Pax3 gene expression impedes cardiac differentiation
- Qiao Li
- , Melanie Le May
- & Jihong Chen
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| Open AccessDiscovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase
- Qing-Hua Hu
- , Ru-Juan Liu
- & En-Duo Wang
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| Open AccessTwo mixed-NH3/amine platinum (II) anticancer complexes featuring a dichloroacetate moiety in the leaving group
- Weiping Liu
- , Jia Su
- & Yan Li
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| Open AccessUltrasound-enhanced delivery of Morpholino with Bubble liposomes ameliorates the myotonia of myotonic dystrophy model mice
- Michinori Koebis
- , Tamami Kiyatake
- & Shoichi Ishiura
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| Open AccessManumycin A corrects aberrant splicing of Clcn1 in myotonic dystrophy type 1 (DM1) mice
- Kosuke Oana
- , Yoko Oma
- & Shoichi Ishiura
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| Open AccessSmall molecule drug screening in Drosophila identifies the 5HT2A receptor as a feeding modulation target
- Gabriel Gasque
- , Stephen Conway
- & Leslie B. Vosshall
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| Open AccessMICE Models: Superior to the HERG Model in Predicting Torsade de Pointes
- James Kramer
- , Carlos A. Obejero-Paz
- & Arthur M. Brown
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| Open AccessA TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain
- Cristina Nativi
- , Roberta Gualdani
- & Stefano Roelens
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| Open AccessMicrotubule Alterations Occur Early in Experimental Parkinsonism and The Microtubule Stabilizer Epothilone D Is Neuroprotective
- Daniele Cartelli
- , Francesca Casagrande
- & Graziella Cappelletti
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| Open AccessNetwork Characteristic Analysis of ADR-related Proteins and Identification of ADR-ADR Associations
- Xiujie Chen
- , Xiangqiong Liu
- & Yuelong Chen
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| Open AccessA Whole Cell Pathway Screen Reveals Seven Novel Chemosensitizers to Combat Chloroquine Resistant Malaria
- Jun-Hong Ch'ng
- , Sachel Mok
- & Kevin Shyong-Wei Tan
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| Open AccessOxymatrine Prevents NF-κB Nuclear Translocation And Ameliorates Acute Intestinal Inflammation
- Javier Rivera Guzman
- , Ja Seol Koo
- & Christian Jobin
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| Open Access1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice
- You-Gui Li
- , Dong-Feng Ji
- & Xin Wang
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| Open AccessDrug addiction is associated with leukocyte telomere length
- Zhaoyang Yang
- , Junyi Ye
- & Yun Liu
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| Open AccessMulticellular Self-Assembled Spheroidal Model of the Blood Brain Barrier
- Eduard Urich
- , Christoph Patsch
- & Per-Ola Freskgård
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| Open AccessDeriving dopaminergic neurons for clinical use. A practical approach
- Rodolfo Gonzalez
- , Ibon Garitaonandia
- & Ruslan A. Semechkin
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| Open AccessCancerDR: Cancer Drug Resistance Database
- Rahul Kumar
- , Kumardeep Chaudhary
- & Gajendra P. S. Raghava
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| Open AccessSecreted Threonyl-tRNA synthetase stimulates endothelial cell migration and angiogenesis
- Tamara F. Williams
- , Adam C. Mirando
- & Karen M. Lounsbury
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| Open AccessAn optical assay of the transport activity of ClC-7
- Ilaria Zanardi
- , Giovanni Zifarelli
- & Michael Pusch
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| Open AccessPost-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective function in lissencephaly
- Shiori Toba
- , Yasuhisa Tamura
- & Shinji Hirotsune
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| Open AccessInhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway
- Hee Jung Kim
- , Jae Seok Jeong
- & Yong Chul Lee
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| Open AccessA cell-based screening system for influenza A viral RNA transcription/replication inhibitors
- Makoto Ozawa
- , Masayuki Shimojima
- & Yoshihiro Kawaoka
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| Open AccessDiscovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity
- Natalia Realini
- , Carlos Solorzano
- & Daniele Piomelli
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| Open AccessBlockade of CD47 increases survival of mice exposed to lethal total body irradiation
- David R. Soto-Pantoja
- , Lisa A. Ridnour
- & David D. Roberts
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| Open AccessEndogenous Cardiac Troponin T Modulates Ca2+-Mediated Smooth Muscle Contraction
- Shunichi Kajioka
- , Fumi Takahashi-Yanaga
- & Seiji Naito
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| Open AccessTarget proteins of ganoderic acid DM provides clues to various pharmacological mechanisms
- Jie Liu
- , Kuniyoshi Shimizu
- & Ryuichiro Kondo
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| Open AccessPharmacological inhibition of TLR4-NOX4 signal protects against neuronal death in transient focal ischemia
- Yukiya Suzuki
- , Kozo Hattori
- & Hideaki Hara
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| Open AccessRelease of Cyclic Phosphatidic Acid from Gelatin-based Hydrogels Inhibit Colon Cancer Cell Growth and Migration
- Tamotsu Tsukahara
- & Kimiko Murakami-Murofushi
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| Open AccessCerebrospinal Fluid Metabolome in Mood Disorders-Remission State has a Unique Metabolic Profile
- Rima Kaddurah-Daouk
- , Peixiong Yuan
- & Wayne Drevets
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| Open AccessChemical Structure of Retro-2, a Compound That Protects Cells against Ribosome-Inactivating Proteins
- Jewn Giew Park
- , Jennifer Nielsen Kahn
- & Yuan-Ping Pang
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| Open AccessArachidonic Acid Enhances Caffeine-Induced Cell Death via Caspase-Independent Cell Death
- Hidekazu Kuwayama
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| Open AccessDiosgenin is an exogenous activator of 1,25D3-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice
- Chihiro Tohda
- , Takuya Urano
- & Tomoharu Kuboyama
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| Open AccessHypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors
- Alexis Bretteville
- , François Marcouiller
- & Emmanuel Planel
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| Open AccessReal-time monitoring in three-dimensional hepatocytes reveals that insulin acts as a synchronizer for liver clock
- Daisuke Yamajuku
- , Takahiko Inagaki
- & Hiroaki Oda
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| Open AccessOxytocin attenuates feelings of hostility depending on emotional context and individuals' characteristics
- Tetsu Hirosawa
- , Mitsuru Kikuchi
- & Yoshio Minabe
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| Open AccessTRPA1 Contributes to the Acute Inflammatory Response and Mediates Carrageenan-Induced Paw Edema in the Mouse
- Lauri J. Moilanen
- , Mirka Laavola
- & Eeva Moilanen
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| Open AccessMultiple tyrosine metabolites are GPR35 agonists
- Huayun Deng
- , Haibei Hu
- & Ye Fang
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| Open AccessAssessment of Extracts from Red Yeast Rice for Herb-Drug Interaction by in-vitro and in-vivo assays
- Wai To Fung
- , G. Subramaniam
- & Pak Ho Henry Leung
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| Open AccessIdentification of links between small molecules and miRNAs in human cancers based on transcriptional responses
- Wei Jiang
- , Xiaowen Chen
- & Xia Li
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| Open AccessEssential role of microfibrillar-associated protein 4 in human cutaneous homeostasis and in its photoprotection
- Shinya Kasamatsu
- , Akira Hachiya
- & Yoshinori Takema
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| Open AccessSystemic aminoglycosides are trafficked via endolymph into cochlear hair cells
- Hongzhe Li
- & Peter S. Steyger
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| Open AccessVisualization of plasmid delivery to keratinocytes in mouse and human epidermis
- Emilio González-González
- , Yeu-Chun Kim
- & Roger L. Kaspar
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Article
| Open AccessPhosphatidylinositol 4,5-bisphosphate (PIP2) controls magnesium gatekeeper TRPM6 activity
- Jia Xie
- , Baonan Sun
- & Lixia Yue
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Article
| Open AccessGalantamine improves olfactory learning in the Ts65Dn mouse model of Down syndrome
- Fabio M. Simoes de Souza
- , Nicolas Busquet
- & Diego Restrepo
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| Open AccessThe metabolic footprint of aging in mice
- Riekelt H. Houtkooper
- , Carmen Argmann
- & Johan Auwerx
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| Open AccessAn N-methyl-d-aspartate receptor agonist facilitates sleep-independent synaptic plasticity associated with working memory capacity enhancement
- Kenichi Kuriyama
- , Motoyasu Honma
- & Yoshiharu Kim