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Article
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Evaluation of molecular inhibitors of loop-mediated isothermal amplification (LAMP)
- May Khat Nwe
- , Nisachon Jangpromma
- & Lapatrada Taemaitree
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Article
| Open Access
Solving the mystery of the FMC63-CD19 affinity
- Jacqueline Seigner
- , Charlotte U. Zajc
- & Michael W. Traxlmayr
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| Open Access
Exploring the hemicellulolytic properties and safety of Bacillus paralicheniformis as stepping stone in the use of new fibrolytic beneficial microbes
- Serigne Inssa Ngom
- , Soufiane Maski
- & Christel Béra-Maillet
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Article
| Open Access
A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity
- Daniel Stern
- , Tanja C. Meyer
- & Brigitte G. Dorner
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Article
| Open Access
VarLOCK: sequencing-independent, rapid detection of SARS-CoV-2 variants of concern for point-of-care testing, qPCR pipelines and national wastewater surveillance
- Xinsheng Nan
- , Patrick Hardinge
- & Tomasz P. Jurkowski
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Article
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Current status of phosphine resistance in Indian field populations of Tribolium castaneum and its influence on antioxidant enzyme activities
- Satyapriya Singh
- , Suresh M. Nebapure
- & Sabtharishi Subramanian
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Article
| Open Access
A cell-based assay for rapid assessment of ACE2 catalytic function
- Warren M. Meyers
- , Ryan J. Hong
- & Kurt Haas
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Article
| Open Access
Micro- and nanochamber array system for single enzyme assays
- Kazuki Iijima
- , Noritada Kaji
- & Yoshinobu Baba
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Article
| Open Access
Anti-nanodisc antibodies specifically capture nanodiscs and facilitate molecular interaction kinetics studies for membrane protein
- Fuhito Nakagawa
- , Marin Kikkawa
- & Satoshi Ogasawara
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| Open Access
Development of a fast and precise potency test for BCG vaccine viability using flow cytometry compared to MTT and colony-forming unit assays
- Hend M. Moghawry
- , Mohamed E. Rashed
- & Tarek Dishisha
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| Open Access
GATS tag system is compatible with biotin labelling methods for protein analysis
- Kohdai Yamada
- , Fumiya Soga
- & Tatsuya Sawasaki
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| Open Access
DARPins bind their cytosolic targets after having been translocated through the protective antigen pore of anthrax toxin
- Lukas Becker
- & Andreas Plückthun
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| Open Access
Haloarchaeal carotenoids exert an in vitro antiproliferative effect on human breast cancer cell lines
- Micaela Giani
- , Yoel Genaro Montoyo-Pujol
- & Rosa María Martínez-Espinosa
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| Open Access
Synthesis and physicochemical characterization of acyl myricetins as potential anti-neuroexocytotic agents
- Sora Cho
- , Byoungjae Kong
- & Dae-Hyuk Kweon
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Article
| Open Access
Contribution of vitamin D3 and thiols status to the outcome of COVID-19 disease in Italian pediatric and adult patients
- Annamaria D’Alessandro
- , Domenico Ciavardelli
- & Ottavia Porzio
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A sputum bioassay for airway eosinophilia using an eosinophil peroxidase aptamer
- M. Monsur Ali
- , Michael G. Wolfe
- & John D. Brennan
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| Open Access
Construction of a bioluminescence-based assay for bitter taste receptors (TAS2Rs)
- Shi Min Tan
- & Wei-Guang Seetoh
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| Open Access
Isolation of a human SARS-CoV-2 neutralizing antibody from a synthetic phage library and its conversion to fluorescent biosensors
- Haimei Li
- , Bo Zhu
- & Hiroshi Ueda
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| Open Access
Establishment of a system evaluating the contractile force of electrically stimulated myotubes from wrinkles formed on elastic substrate
- Hiroki Hamaguchi
- , Tsubasa S. Matsui
- & Yasuko Manabe
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Measuring haemolysis in cattle serum by direct UV–VIS and RGB digital image-based methods
- Belén Larrán
- , Marta López-Alonso
- & Carlos Herrero-Latorre
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Article
| Open Access
A hands-free stool sampling system for monitoring intestinal health and disease
- Sonia Grego
- , Claire M. Welling
- & Brian R. Stoner
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Article
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Effect of thermal and chemical treatments used for SARS-COV-2 inactivation in the measurement of saliva analytes
- Elsa Lamy
- , Camila P. Rubio
- & Asta Tvarijonaviciute
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Ultrasensitive detection of salivary SARS-CoV-2 IgG antibodies in individuals with natural and COVID-19 vaccine-induced immunity
- Stefani N. Thomas
- , Amy B. Karger
- & Bharat Thyagarajan
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The use of high-affinity polyhistidine binders as masking probes for the selection of an NDM-1 specific aptamer
- Wiebke Sabrowski
- , Nico Dreymann
- & Marcus M. Menger
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Investigation and validation of labelling loop mediated isothermal amplification (LAMP) products with different nucleotide modifications for various downstream analysis
- Christian Warmt
- , Ceren Yaslanmaz
- & Jörg Henkel
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| Open Access
Exploring carbohydrate binding module fusions and Fab fragments in a cellulose-based lateral flow immunoassay for detection of cystatin C
- Satheesh Natarajan
- , Jayaraj Joseph
- & Duarte Miguel França Prazeres
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| Open Access
Acacia senegal gum attenuates systemic toxicity in CCl4-intoxicated rats via regulation of the ROS/NF-κB signaling pathway
- Marwa M. Abu-Serie
- , Asmaa F. Hamouda
- & Noha H. Habashy
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| Open Access
Sensitive and quantitative detection of cardiac troponin I with upconverting nanoparticle lateral flow test with minimized interference
- Sherif Bayoumy
- , Iida Martiskainen
- & Kim Pettersson
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| Open Access
Development of an automated system to measure ion channel currents using a surface-modified gold probe
- Minako Hirano
- , Masahisa Tomita
- & Toru Ide
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| Open Access
Quantitative spectrofluorometric assay detecting nuclear condensation and fragmentation in intact cells
- Pavlina Majtnerova
- , Jan Capek
- & Tomas Rousar
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Measurements of the swimming speeds of motile microorganisms using object tracking and their correlation with water pollution and rheology levels
- Ashaa Preyadharishini Shunmugam
- , Gowtham Subramanian
- & Javier G. Fernandez
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| Open Access
Phosphopeptide interactions of the Nbs1 N-terminal FHA-BRCT1/2 domains
- Kyungmin Kim
- , Thomas W. Kirby
- & Robert E. London
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| Open Access
Effects of cadmium stress on physiological indexes and fruiting body nutritions of Agaricus brasiliensis
- Lingyun Liu
- , Hua Chen
- & Guoxue Li
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Discovery of novel antituberculosis agents among 3-phenyl-5-(1-phenyl-1H-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazole derivatives targeting aminoacyl-tRNA synthetases
- Mariia Yu. Rybak
- , Anatoliy O. Balanda
- & Galyna P. Volynets
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Extraction of short chain chitooligosaccharides from fungal biomass and their use as promoters of arbuscular mycorrhizal symbiosis
- Andrea Crosino
- , Elisa Moscato
- & Andrea Genre
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Enzyme and lateral flow monoclonal antibody-based immunoassays to simultaneously determine spirotetramat and spirotetramat-enol in foodstuffs
- Ramón E. Cevallos-Cedeño
- , Consuelo Agulló
- & Josep V. Mercader
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Article
| Open AccessBioavailable fluoride in calcium-containing dentifrices
- Peiyan Shen
- , James R. Fernando
- & Eric C. Reynolds
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| Open Access
Cu-chitosan nano-net improves keeping quality of tomato by modulating physio-biochemical responses
- Mahendra Meena
- , Shalini Pilania
- & Vinod Saharan
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| Open Access
Rapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids
- Matthew Sorensen
- , Courtney E. Chandler
- & Erik Nilsson
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| Open Access
Spectral fingerprinting to evaluate effects of storage conditions on biomolecular structure of filter-dried saliva samples and recovered DNA
- Raffaele Brogna
- , Harriëtte Oldenhof
- & Willem F. Wolkers
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| Open Access
A serological assay to detect SARS-CoV-2 antibodies in at-home collected finger-prick dried blood spots
- Donna Grace Karp
- , Kenneth Danh
- & Cheng-ting Tsai
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| Open Access
Modified aptamers as reagents to characterize recombinant human erythropoietin products
- Wojciech Jankowski
- , H. A. Daniel Lagassé
- & Zuben E. Sauna
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Article
| Open Access
Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases
- Kari Kopra
- , Iraida Sharina
- & Harri Härmä
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An optimized desuccinylase activity assay reveals a difference in desuccinylation activity between proliferative and differentiated cells
- Taolin Yuan
- , Jaap Keijer
- & Vincent C. J. de Boer
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Article
| Open Access
Rapid detection of cytochrome cd1-containing nitrite reductase encoding gene nirS of denitrifying bacteria with loop-mediated isothermal amplification assay
- Xuzhi Zhang
- , Qianqian Yang
- & Keming Qu
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Article
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Predominant synthesis of giant myofibrillar proteins in striated muscles of the long-tailed ground squirrel Urocitellus undulatus during interbout arousal
- Svetlana Popova
- , Anna Ulanova
- & Ivan Vikhlyantsev
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The influence of proline isomerization on potency and stability of anti-HIV antibody 10E8
- Miklos Guttman
- , Neal N. Padte
- & Kelly K. Lee
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Editorial
| Open AccessSmall-volume point-of-care analytical methods
Detecting clinically relevant diagnostic biomarkers, suitable for point-of-care detection, may facilitate rapid treatment and prevention of disease. However, medical diagnosis for which there are limited quantities of testable tissue or fluid, require point-of-care technologies with superior sensitivity and specificity. The purpose of this Editorial is to provide an overview of the Collection’s content, comprising original research into fluidics-based diagnostic platforms—specifically those made of paper or other low-cost materials, that can suitably operate with tiny sample volumes from mL to nL. In particular, we will focus on the clinical applications of such research, with potential uses in a number of fields including combating the COVID-19 pandemic for instance.
- Chao-Min Cheng
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Article
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Circulating GFAP and Iba-1 levels are associated with pathophysiological sequelae in the thalamus in a pig model of mild TBI
- Audrey D. Lafrenaye
- , Stefania Mondello
- & Patrick M. Kochanek
Isolation of nucleic acids using liquid–liquid phase separation of pH-sensitive elastin-like polypeptides