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A two-in-one drug that modulates neural pathways involved in appetite and reward might prove to be more effective and longer lasting than current weight-loss drugs on the market.
A design principle for buildings incorporates components that can control the propagation of failure by isolating parts of the structure as they fail — offering a way to prevent a partial collapse snowballing into complete destruction.
Both parents of oldfield mice care for offspring, whereas in deer mice, mothers usually care for pups. The discovery of a type of adrenal-gland cell that is present in oldfield mice but not in deer mice helps to explain the difference.
A book cataloguing mysterious events challenges scientists to provide some answers, and Charles Darwin continues his investigations of crimes against primroses, in the weekly dip into Nature’s archive.
Some genes carry an ‘imprint’ on either the maternal or the paternal copy, which determines whether or not that copy is expressed. This 1984 discovery changed how scientists think about gene regulation and inheritance.
The development of high-performance organic LEDs and other devices that emit near-infrared light has been hindered by seemingly fundamental features of the light-emitting molecules. A potential solution has been identified.
The Chilean soapbark tree is the source of QS-21 — a valuable but hard-to-obtain vaccine additive. Yeast strains engineered to express all components of the QS-21 biosynthetic pathway provide an alternative route to this therapeutic.
What stabilized and strengthened the oldest, most robust blocks of continental crust billions of years ago during the Archaean eon has long been a mystery. It seems that a surprise helping hand might have come from the air above.
Efforts to develop an electronic newspaper providing information at the touch of a button took a step forward 50 years ago, and airborne bacteria in the London Underground come under scrutiny, in the weekly dip into Nature’s archive.
Cardiovascular disease claims more lives each year than do the two next-deadliest diseases combined. An ultrasound technique that tracks tiny gas-filled bubbles could pave the way towards improved early detection.
Some fox species leap up and pounce head first into snow to capture prey that they hear below the surface. An analysis of the forces involved reveals how the shape of the skull has evolved to minimize damage from this behaviour.
By adapting methods for fabricating and testing conventional computer chips, researchers have brought silicon-based quantum computers closer to reality — and to accessing the immense benefits of a mature chipmaking industry.
Genetic sequencing of human kidney cancers worldwide has revealed associations between geographical locations and specific mutation patterns, indicating exposure to known and unknown mutation-promoting agents.
Organelles called mitochondria are transferred to blood-vessel-forming cells by support cells. Unexpectedly, these mitochondria are degraded, kick-starting the production of new ones and boosting vessel formation.
What lessons can we learn from the factors that govern the resilience of human populations? A large-scale analysis examining ancient societies around the world provides a detailed look at what drives sustainability.
An innovative proposal to stop exam over-preparation, plus William Bateson’s 1924 take on the previous century of biology, in the weekly dip into Nature’s archive.
A highly precise timekeeping instrument has been adapted for the real world. The compact and robust device is smaller than its commercial counterparts and performs comparably in the laboratory and aboard a naval ship.
A therapeutic strategy that alters gene expression in a rare and severe neurodevelopmental condition has been tested in stem-cell-based models of the disease, and has been shown to correct genetic and cellular defects.
Cells grown on a 3D scaffold have generated a ‘mini-colon’ that mimics key features of the organ. Controlled expression of cancer-associated genes in the system offers a way to examine tumour formation over space and time.
Genetic pedigrees spanning nine generations uncover the social organization of a nomadic empire that dominated much of central and eastern Europe from the sixth to the early ninth century.
