Tumour biomarkers articles within Nature Materials

Featured

• Article | 30 November 2020

  Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression

  It is now shown that tumour-associated macrophages recruited early during tumour evolution stimulate stromal fibroblasts to express collagen crosslinking enzymes and that the stromal expression, particularly of lysyl hydroxylase 2, can predict survival in a patient cohort.

  • Ori Maller
  • , Allison P. Drain
  •  & Valerie M. Weaver

• News & Views | 25 October 2017

  Treasure trove for cancer medicine

  Fragments of DNA that are derived from dead tumour cells and shed into a patient's blood have been utilized as biomarkers for the diagnosis and prognosis of liver cancer.

  • Miljana Tanić
  •  & Stephan Beck

• Article | 09 October 2017

  Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma

  Circulating tumour DNA is used as a biomarker for cancer diagnosis. Here, the authors identified a DNA methylation biomarker for hepatocellular carcinoma and developed diagnostic and prognostic models to predict specificity and survival of patients.

  • Rui-hua Xu
  • , Wei Wei
  •  & Kang Zhang