Lineage tracking articles within Nature

Featured

  • News |

    The master builders that underlie tumour growth may inform treatment strategies.

    • Monya Baker

  • News & Views |

    Developing organs adapt dynamically to meet the changing needs of a growing organism. A study in zebrafish reveals surprising patterns of muscle growth that reshape the heart as it matures. See Article p.479

    • Deborah Yelon

  • Letter |

    One of two papers showing the generation of haematopoietic stem cells (HSCs) from the ventral wall of the dorsal aorta in live zebrafish embryos. Here, combined fluorescent reporter transgenes, confocal time-lapse microscopy and flow cytometry identify and isolate the stepwise intermediates as aortic haemogenic endothelium transitions to nascent HSCs. HSCs generated from this haemogenic endothelium are the lineal founders of virtually all of the adult haematopoietic system.

    • Julien Y. Bertrand
    • , Neil C. Chi
    •  & David Traver

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