Genetic mapping articles within Nature Communications

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  • Article
    | Open Access

    The lack of large-scale QTL cloning method hampers systematic dissection of genetic base of quantitative traits. Here, the authors develop a multi-omics data-based technique for large-scale and rapid cloning of quantitative genes of tassel branch number and discovery of selection signatures in maize breeding.

    • Xi Wang
    • , Juan Li
    •  & Lin Li

  • Article
    | Open Access

    Rice grain shape or size is an important trait associated with both yield and appearance quality. Here, the authors identify GS9 as a negative transcription regulator of slender grain and show it can improve grain shape and appearance independently from other previously identified grain size genes.

    • Dong-Sheng Zhao
    • , Qian-Feng Li
    •  & Qiao-Quan Liu

  • Article
    | Open Access

    The domestic dog is an important model organism for our understanding of cancer and other diseases. Here the authors conduct a genome-wide association study across multiple breeds and identify novel loci significantly associated with several complex diseases and morphological traits.

    • Jessica J. Hayward
    • , Marta G. Castelhano
    •  & Adam R. Boyko

  • Article
    | Open Access

    Adenosine-to-inosine (A-to-I) RNA editing plays an important role in neurological functions. Here, by a quantitative trait loci (QTL) mapping approach in 131 Drosophila melanogasterstrains, the authors identify 545 QTLs associated with differences in RNA editing.

    • Gokul Ramaswami
    • , Patricia Deng
    •  & Jin Billy Li

  • Article |

    Expression quantitative trait loci (eQTLs) may provide insight into the functional mechanisms underlying disease risk variants. Here the authors characterize INDEL-specific eQTLs in several tissues and show that these can have both tissue-specific and tissue-consistent effects.

    • Jinyan Huang
    • , Jun Chen
    •  & Liming Liang

  • Article
    | Open Access

    Structural variations in crop genomes are thought to be responsible for significant differences in phenotype and they can be well-represented by a ‘pan-genome’. Here, Lu et al.develop an approach to genetically map pan-genome sequence anchors using 14,129 inbred lines of maize, showing structural variation is a significant source of adaptive variation.

    • Fei Lu
    • , Maria C. Romay
    •  & Edward S. Buckler

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