News & Views |
Featured
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Article |
Self-organizing optic-cup morphogenesis in three-dimensional culture
Organogenesis relies on the orchestration of many cellular interactions to create the collective cell behaviours that progressively shape developing tissues. Using a three-dimensional embryonic stem cell culture system, this study successfully generated neural retinal tissues that formed a fully stratified neural retinal structure with all the major components located in their proper spatial location as seen during optic-cup development in vivo. This approach might have important implications for stem cell therapy for retinal repair.
- Mototsugu Eiraku
- , Nozomu Takata
- & Yoshiki Sasai
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News |
Sperm grown in a test tube
Immature mouse testicles yield fully developed sperm in culture.
- Janelle Weaver
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Research Highlights |
Bioengineering: Cell culture on a chip
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