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Open Access
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A high-performance neuroprosthesis for speech decoding and avatar control
A study using high-density surface recordings of the speech cortex in a person with limb and vocal paralysis demonstrates real-time decoding of brain activity into text, speech sounds and orofacial movements.
- Sean L. Metzger
- , Kaylo T. Littlejohn
- & Edward F. Chang
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Article
| Open Access
Walking naturally after spinal cord injury using a brain–spine interface
A reliable digital bridge restored communication between the brain and spinal cord and enabled natural walking in a participant with spinal cord injury.
- Henri Lorach
- , Andrea Galvez
- & Grégoire Courtine
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Article |
High-performance brain-to-text communication via handwriting
A brain–computer interface enables rapid communication through neural decoding of attempted handwriting movements in a person with paralysis.
- Francis R. Willett
- , Donald T. Avansino
- & Krishna V. Shenoy
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Article |
Decoding and perturbing decision states in real time
In macaque motor cortex, moment-to-moment fluctuations in neurally derived decision variables are tightly linked to decision state and predict behavioural choices with better accuracy than condition-averaged decision variables or the visual stimulus alone, and can be used to distinguish between different models of decision making.
- Diogo Peixoto
- , Jessica R. Verhein
- & William T. Newsome
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Article |
Speech synthesis from neural decoding of spoken sentences
A neural decoder uses kinematic and sound representations encoded in human cortical activity to synthesize audible sentences, which are readily identified and transcribed by listeners.
- Gopala K. Anumanchipalli
- , Josh Chartier
- & Edward F. Chang
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Letter |
Restoring cortical control of functional movement in a human with quadriplegia
Signals recorded from motor cortex—through an intracortical implant—can be linked in real-time to activation of forearm muscles to restore movement in a paralysed human.
- Chad E. Bouton
- , Ammar Shaikhouni
- & Ali R. Rezai
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Research Highlights |
Brain–machine does the two-step
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News |
Mind-controlled robot arms show promise
People with tetraplegia use their thoughts to control robotic aids.
- Alison Abbott
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Letter |
Restoration of grasp following paralysis through brain-controlled stimulation of muscles
A functional electrical stimulation system in primates that is controlled by recordings made from microelectrodes permanently implanted in the brain can be used to control the intensity of stimulation of muscles that are temporarily paralysed by pharmacological motor nerve blockade, thereby restoring voluntary control of the affected muscles; this is a major advance towards similar restoration of hand function in human patients with spinal cord injury.
- C. Ethier
- , E. R. Oby
- & L. E. Miller
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News & Views |
How brains learn to control machines
After training, animals and humans can make their thoughts interact directly with computers. A study provides evidence that the corticostriatal system of the brain is essential for this learning process.
- David T. Blake
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Letter |
Corticostriatal plasticity is necessary for learning intentional neuroprosthetic skills
A novel study in rodents suggests that corticostriatal plasticity is necessary for abstract skill learning.
- Aaron C. Koralek
- , Xin Jin
- & Jose M. Carmena
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News |
Monkey brains 'feel' virtual objects
Macaques use a brain-controlled virtual hand to identify artificial texture of objects.
- Susan Young
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Letter |
Active tactile exploration using a brain–machine–brain interface
- Joseph E. O’Doherty
- , Mikhail A. Lebedev
- & Miguel A. L. Nicolelis
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News |
Music is all in the mind
A brain–computer interface allows paralysed patients to play music with brainpower alone.
- Philip Ball
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News |
'Marilyn Monroe' neuron aids mind control
Volunteers fade famous images in and out using a 'brain–machine' interface.
- Alison Abbott
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News |
No gain from brain training
Computerized mental workouts don't boost mental skills, study claims.
- Alla Katsnelson
A high-performance speech neuroprosthesis