Bone marrow cells articles within Nature Communications

Featured

• Article
  09 August 2023 | Open Access

  Bone marrow adiposity modulation after long duration spaceflight in astronauts

  Bone marrow adiposity is linked to disease, and it is unknown how it is modulated during space travel. Here, the authors show that astronauts returning from ISS missions had decreased marrow fat and increased hematopoiesis and bone formation, suggesting that adipose reserves in the bone marrow might be used as an energy source to counteract anemia and bone loss associated with space flight.

  • Tammy Liu
  • , Gerd Melkus
  •  & Guy Trudel

• Article
  08 February 2019 | Open Access

  Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

  The diversity of fibroblasts contributing to wound healing is unclear. Here, the authors use single-cell RNA-sequencing to identify heterogeneity among murine fibroblasts in the wound and find that recruited myeloid cells contribute to adipocyte regeneration during healing.

  • Christian F. Guerrero-Juarez
  • , Priya H. Dedhia
  •  & Maksim V. Plikus

• Article
  19 May 2015 | Open Access

  Exposure to a youthful circulation rejuvenates bone repair through modulation of β-catenin

  The reparative capacity of tissues decreases with age. Here, Baht et al. perform parabiosis experiments and provide evidence for the existence of a soluble factor produced by young, but not old, haematopoietic cells that is capable of improving fracture repair in old mice.

  • Gurpreet S. Baht
  • , David Silkstone
  •  & Benjamin A. Alman