Adjuvants articles within Scientific Reports

Featured

• Article
  04 February 2024 | Open Access

  Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

  • Felicia N. Watson
  • , Melanie J. Shears
  •  & Sean C. Murphy

• Article
  23 February 2023 | Open Access

  Advances on the early cellular events occurring upon exposure of human macrophages to aluminum oxyhydroxide adjuvant

  • J.-D. Masson
  • , G. Badran
  •  & G. Crépeaux

• Article
  08 December 2022 | Open Access

  Effective adjuvantation of nanograms of influenza vaccine and induction of cross-protective immunity by physical radiofrequency adjuvant

  • Zhuofan Li
  • , Xinliang Kang
  •  & Xinyuan Chen

• Article
  18 October 2022 | Open Access

  Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination

  • David J. Dowling
  • , Soumik Barman
  •  & Jay T. Evans

• Article
  21 September 2022 | Open Access

  ZIKV-envelope proteins induce specific humoral and cellular immunity in distinct mice strains

  • Victória Alves Santos Lunardelli
  • , Juliana de Souza Apostolico
  •  & Daniela Santoro Rosa

• Article
  20 July 2022 | Open Access

  Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems

  • Laura A. J. Feather
  • , Vinod Nadella
  •  & Andrew Devitt

• Article
  13 June 2022 | Open Access

  Intranasal immunization with a proteosome-adjuvanted SARS-CoV-2 spike protein-based vaccine is immunogenic and efficacious in mice and hamsters

  • Felicity C. Stark
  • , Bassel Akache
  •  & Martin Handfield

• Article
  02 June 2022 | Open Access

  Magnitude and breadth of antibody cross-reactivity induced by recombinant influenza hemagglutinin trimer vaccine is enhanced by combination adjuvants

  • Jenny E. Hernandez-Davies
  • , Emmanuel P. Dollinger
  •  & D. Huw Davies

• Article
  09 May 2022 | Open Access

  Army liposome formulation containing QS-21 render human monocyte-derived macrophages less permissive to HIV-1 infection by upregulating APOBEC3A

  • Ousman Jobe
  • , Jiae Kim
  •  & Mangala Rao

• Article
  17 November 2021 | Open Access

  Oral vaccination of piglets against Mycoplasma hyopneumoniae using silica SBA-15 as an adjuvant effectively reduced consolidation lung lesions at slaughter

  • Marina L. Mechler-Dreibi
  • , Henrique M. S. Almeida
  •  & Luís Guilherme de Oliveira

• Article
  09 November 2021 | Open Access

  An integrated computational framework to design a multi-epitopes vaccine against Mycobacterium tuberculosis

  • Aqel Albutti

• Article
  08 November 2021 | Open Access

  Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant

  • Bassel Akache
  • , Tyler M. Renner
  •  & Michael J. McCluskie

• Article
  19 July 2021 | Open Access

  Ex vivo dendritic cell-based (DC) vaccine pulsed with a low dose of liposomal antigen and CpG-ODN improved PD-1 blockade immunotherapy

  • Mona Yazdani
  • , Zahra Gholizadeh
  •  & Ali Badiee

• Article
  30 April 2021 | Open Access

  miR-451a levels rather than human papillomavirus vaccine administration is associated with the severity of murine experimental autoimmune encephalomyelitis

  • Momoka Nakashima
  • , Kana Ishikawa
  •  & Hiroyuki Oshiumi

• Article
  12 January 2021 | Open Access

  The association of Coronavirus Disease-19 mortality and prior bacille Calmette-Guerin vaccination: a robust ecological analysis using unsupervised machine learning

  • Nathan A. Brooks
  • , Ankur Puri
  •  & Ashish M. Kamat

• Article
  16 December 2020 | Open Access

  Mucosal IL-4R antagonist HIV vaccination with SOSIP-gp140 booster can induce high-quality cytotoxic CD4⁺/CD8⁺ T cells and humoral responses in macaques

  • Z. Li
  • , M. Khanna
  •  & C. Ranasinghe

• Article
  23 November 2020 | Open Access

  A novel Schmallenberg virus subunit vaccine candidate protects IFNAR^-/- mice against virulent SBV challenge

  • Hani Boshra
  • , Gema Lorenzo
  •  & Nicola G. A. Abrescia

• Article
  13 October 2020 | Open Access

  Synthetic Biology-derived triterpenes as efficacious immunomodulating adjuvants

  • Mizuki Tateno
  • , Barbara J. Stone
  •  & Chase F. Kempinski

• Article
  20 August 2020 | Open Access

  RhCMV serostatus and vaccine adjuvant impact immunogenicity of RhCMV/SIV vaccines

  • W. L. William Chang
  • , Jesse D. Deere
  •  & Ellen E. Sparger

• Article
  03 August 2020 | Open Access

  Impact of vaccine type on HIV-1 vaccine elicited antibody durability and B cell gene signature

  • Rohith Palli
  • , Kelly E. Seaton
  •  & Juilee Thakar

• Article
  25 June 2020 | Open Access

  Plant virus particles with various shapes as potential adjuvants

  • Ekaterina A. Evtushenko
  • , Ekaterina M. Ryabchevskaya
  •  & Olga V. Karpova

• Article
  21 May 2020 | Open Access

  Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy

  • Yi-Ju Chou
  • , Ching-Cheng Lin
  •  & Shu-Ling Fu

• Article
  01 April 2020 | Open Access

  Combination therapy using human papillomavirus L1/E6/E7 genes and archaeosome: a nanovaccine confer immuneadjuvanting effects to fight cervical cancer

  • Hesam Karimi
  • , Hoorieh Soleimanjahi
  •  & Razieh Sadat Banijamali

• Article
  23 January 2020 | Open Access

  Adjuvant-free immunization with infective filarial larvae as lymphatic homing antigen carriers

  • Catherine Card
  • , David S. Wilson
  •  & Witold W. Kilarski

• Article
  22 October 2019 | Open Access

  LTA1 is a safe, intranasal enterotoxin-based adjuvant that improves vaccine protection against influenza in young, old and B-cell-depleted (μMT) mice

  • E. Valli
  • , A. J. Harriett
  •  & E. B. Norton

• Article
  01 October 2019 | Open Access

  Inactivated alpha toxin from Clostridium novyi type B in nano-emulsion protect partially protects Swiss mice from lethal alpha toxin challenge

  • Mellanie Karoline C. Felix
  • , Tullio T. Deusdará
  •  & Alex Sander R. Cangussu

• Article
  08 August 2019 | Open Access

  The droplet size of emulsion adjuvants has significant impact on their potency, due to differences in immune cell-recruitment and -activation

  • Ruchi R. Shah
  • , Marianna Taccone
  •  & Anja Seubert

• Article
  03 June 2019 | Open Access

  Combination of TLR2 and TLR3 agonists derepress infectious bursal disease virus vaccine-induced immunosuppression in the chicken

  • Khalid Bashir
  • , Deepthi Kappala
  •  & Saravanan Ramakrishnan

• Article
  05 April 2019 | Open Access

  Mucosal and systemic SIV-specific cytotoxic CD4⁺ T cell hierarchy in protection following intranasal/intramuscular recombinant pox-viral vaccination of pigtail macaques

  • Mayank Khanna
  • , Ronald J. Jackson
  •  & Charani Ranasinghe

• Article
  30 November 2018 | Open Access

  Identification of Immune Signatures of Novel Adjuvant Formulations Using Machine Learning

  • Sidhartha Chaudhury
  • , Elizabeth H. Duncan
  •  & Elke S. Bergmann-Leitner

• Article
  09 October 2018 | Open Access

  Development of a Molecular Adjuvant to Enhance Antigen-Specific CD8⁺ T Cell Responses

  • Benedict R. Halbroth
  • , Sarah Sebastian
  •  & Alexandra J. Spencer

• Article
  02 October 2018 | Open Access

  Cationic domains in particle-forming and assembly-deficient HBV core antigens capture mammalian RNA that stimulates Th1-biased antibody responses by DNA vaccination

  • Jana Krieger
  • , Katja Stifter
  •  & Reinhold Schirmbeck

• Article
  11 September 2018 | Open Access

  Quillaja brasiliensis saponin-based nanoparticulate adjuvants are capable of triggering early immune responses

  • Samuel Paulo Cibulski
  • , Mariana Rivera-Patron
  •  & Fernando Silveira

• Article
  30 July 2018 | Open Access

  Aluminum salts as an adjuvant for pre-pandemic influenza vaccines: a meta-analysis

  • Yu-Ju Lin
  • , Yun-Jui Shih
  •  & Chi-Tai Fang

• Article
  16 July 2018 | Open Access

  A CpG-adjuvanted intranasal enterovirus 71 vaccine elicits mucosal and systemic immune responses and protects human SCARB2-transgenic mice against lethal challenge

  • Yu-Li Lin
  • , Yen-Hung Chow
  •  & Bor-Luen Chiang

• Article
  24 May 2018 | Open Access

  Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity

  • A. A. Latanova
  • , S. Petkov
  •  & M. G. Isaguliants

• Article
  05 February 2018 | Open Access

  Intracellular tracing of amyloid vaccines through direct fluorescent labelling

  • Matthew Mold
  • , Manpreet Kumar
  •  & Christopher Exley

• Article
  07 December 2017 | Open Access

  Co-expression of mFat-1 and pig IGF-1 genes by recombinant plasmids in modified chitosan nanoparticles and its synergistic effect on mouse immunity

  • Qi Xiong
  • , Jianlin Chen
  •  & Rong Gao

• Article
  09 November 2017 | Open Access

  Toxoplasma gondii tachyzoite-extract acts as a potent immunomodulator against allergic sensitization and airway inflammation

  • Mirjana Drinić
  • , Angelika Wagner
  •  & Irma Schabussova

• Article
  27 October 2017 | Open Access

  Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors

  • Yingjie Nie
  • , De Yang
  •  & Joost J. Oppenheim

• Article
  17 October 2017 | Open Access

  Efficient induction of comprehensive immune responses to control pathogenic E. coli by clay nano-adjuvant with the moderate size and surface charge

  • Weiyu Chen
  • , Huali Zuo
  •  & Zhi Ping Xu

• Article
  09 October 2017 | Open Access

  Quantifying the relative immune cell activation from whole tissue/organ-derived differentially expressed gene data

  • Edward Wijaya
  • , Yoshinobu Igarashi
  •  & Taiki Aoshi

• Article
  18 September 2017 | Open Access

  Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo

  • Stefan Schülke
  • , Kirsten Kuttich
  •  & Stephan Scheurer

• Article
  17 August 2017 | Open Access

  Cytolytic DNA vaccine encoding lytic perforin augments the maturation of- and antigen presentation by- dendritic cells in a time-dependent manner

  • Danushka K. Wijesundara
  • , Wenbo Yu
  •  & Branka Grubor-Bauk

• Article
  17 August 2017 | Open Access

  Delta inulin-based adjuvants promote the generation of polyfunctional CD4⁺ T cell responses and protection against Mycobacterium tuberculosis infection

  • Claudio Counoupas
  • , Rachel Pinto
  •  & James A. Triccas

• Article
  04 August 2017 | Open Access

  Adjuvanting a viral vectored vaccine against pre-erythrocytic malaria

  • Anita Milicic
  • , Christine S. Rollier
  •  & Arturo Reyes-Sandoval

• Article
  24 July 2017 | Open Access

  A new marine-derived sulfoglycolipid triggers dendritic cell activation and immune adjuvant response

  • Emiliano Manzo
  • , Adele Cutignano
  •  & Angelo Fontana

• Article
  19 July 2017 | Open Access

  Alternatives to mineral oil adjuvants in vaccines against Aeromonas salmonicida subsp. salmonicida in rainbow trout offer reductions in adverse effects

  • Kasper Rømer Villumsen
  • , Erling Olaf Koppang
  •  & Anders Miki Bojesen

• Article
  31 May 2017 | Open Access

  Combinatorial Delivery of Dual and Triple TLR Agonists via Polymeric Pathogen-like Particles Synergistically Enhances Innate and Adaptive Immune Responses

  • Ranjna Madan-Lala
  • , Pallab Pradhan
  •  & Krishnendu Roy

• Article
  11 May 2017 | Open Access

  The S. aureus 4-oxalocrotonate tautomerase SAR1376 enhances immune responses when fused to several antigens

  • Pauline M. van Diemen
  • , Darren B. Leneghan
  •  & David H. Wyllie