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Researchers in China and South Korea have developed a rapid immunodot assay to detect aquaporin 4-targeting IgG autoantibodies in the serum of individuals with neuromyelitis optica spectrum disorder.
Two new studies have provided important mechanistic insights into TDP-43 pathology, a hallmark of neurodegenerative conditions such as amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
A new study identifies LONRF2 as a protein quality control ubiquitin ligase that is induced in senescent neurons and seems to protect them against degeneration