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This study reports that human BTN3A3 restricts replication of avian influenza A viruses (IAVs) but not human IAVs, and that BTN3A3 evasion promotes spillover into humans.
The authors developed a refillable, long-acting subcutaneous nanofluidic antiretroviral delivery implant that conferred protection against infection with simian–human immunodeficiency virus in rhesus macaques.
In this study, Irazoki et al. show that Vibrio cholerae releases d-amino acids into the environment, which are sensed by a bacterial chemoreceptor to prompt a repellent chemotactic response.
In this study, Tsuji et al. report the glycolipid 7DW8-5 that exploits the host innate immune system to control SARS-CoV-2, respiratory syncytial virus and influenza virus infections.
In this study, Gül et al. show that usage of different carbon sources by Enterobacteriaceae strains determines their expansion and co-existence in the mouse gut and favours plasmid transfer.
In this Review, Stride and co-workers discuss emerging drug delivery strategies that are explored in antibiofilm therapy to improve the clinical efficacy of antibiofilm agents, highlighting their current limitations and future prospects.
In this Review, Lemon and colleagues describe quasi-enveloped virions, how they enter and how they are released from the human host cell, and how they affect host immunity and pathogenesis.
Over the course of the lifespan of a host, the gut microbiota undergoes evolutionary changes and is shaped by ecological interactions with the host and other microbial species. In this Review, Barreto and Gordo explore mechanisms of evolution of the gut microbiota, intrahost evolution of strains and communities and implications of intrahost evolution for disease and microbiota-based therapies.
In this Review, Wang, Gao and Aksoy delve into the influence of microbiota on vector physiology and competence, provide an overview of the common and unique characteristics of microbiota in major disease vector systems and examine the potential applications of manipulating vector microbiota for vector control purposes.
