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Two new studies provide insights into the close association betweenWolbachiaspp. and their hosts; one shows plant-mediated transmission and the other the bacterial origin of a new host sex chromosome.
This study identifies 1,445 RNA viruses in invertebrate animals, including new virus families, and uncovers unexpected levels of evolutionary flexibility.
This study shows that the bacterial effector Sca4 promotes intercellular spread of the obligate intracellular pathogenRickettsia parkeriby disrupting the transmission of intercellular tension at cell–cell adherence junctions.
This study reveals that ribosomal antibiotics function in a context-specific manner, dependent on the penultimate amino acid in the nascent chain and the amino acid in the P-site of the peptidyl transferase center.
This study investigated the role of IFITM proteins in the restriction of HIV-1 strains that have different receptor tropism and identified IFITM proteins as major effectors of the innate immune response.
This study reports that the DENV non-structural protein NS4B induces elongation of mitochondria, and that this is linked to the formation of convoluted membranes, enhanced viral replication and impaired immune responses.
This study shows that dynamic pores in the capsid of HIV allow the import of substrates for reverse transcription, thereby shielding the reaction from the host cytosol.