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This Review highlights how obesity and impaired metabolic health increase complications and mortality in coronavirus disease 2019 (COVID-19) and summarizes the consequences of infection with severe acute respiratory syndrome coronavirus 2 for organ function. In addition, there is a discussion on the implications of the COVID-19 pandemic for the obesity pandemic.
This Review focuses on the current understanding of the molecular and cellular pathology of diabetic retinopathy. The primary focus is on the cellular signalling between the neuronal and vascular retina that promotes formation of the inner blood–retinal barrier of the retinal vasculature as an important point of intervention.