Collections

Filters ​

  • Collection |

    This Collection of articles from Nature Reviews EndocrinologyandNature Reviews Rheumatologycovers the interesting developments within the field of osteoporosis research and includes articles on the clinical assessment of patients with osteoporosis, approaches for the prevention and management of this disease, as well as the impact of osteoporosis on health and economics worldwide.

  • Focus |

    Celiac disease is an intestinal inflammatory disorder that occurs in genetically predisposed individuals and causes intolerance to wheat protein gluten and related proteins (prolamines) that are contained in barley and rye. Histologically, the small bowel mucosa in celiac disease shows villous atrophy (lost of villi), crypt hyperplasia and lymphocyte infiltration. To allow better understand the histological damage that occurs during mucosal changes Marsh proposed a series of stages to aid diagnostics: Marsh I represents lymphocytic enteritis, Marsh II represents lymphocytic enteritis with crypt hyperplasia, and Marsh III represents partial (a), subtotal (b) and total (c) villous atrophy. These changes are accompanied by a gradual increase in the number of T cells and activation of immunoregulatory counteractions in the diseased mucosa. The March 2011 special issue on celiac sprue and mucosal immunity presents some of the latest advances in celiac disease diagnostics; the web focus further expands our understanding of this inflammatory disorder through a collection of recent articles from across Springer Nature.

  • Focus |

    This Focus issue on pituitary tumors includes specially commissioned articles that translate the latest pathogenesis and management insights into clinical practice. Identified by leaders in the field as promising areas in pituitary research, the Focus issue provides a valuable and cutting-edge resource for clinicians and researchers alike.

  • Focus |

    This Focus issue on thyroid cancer includes specially commissioned articles discussing the pathophysiology of thyroid neoplasia and current and future clinical management strategies. The topics covered were identified by leaders in the field as promising areas in thyroid cancer research and clinical practice, making the Focus issue a valuable resource for investigators and practitioners alike.

  • Focus |

    This Focus on noninsulin therapies for type 1 diabetes mellitus (T1DM) includes a series of specially commissioned articles that introduce some novel approaches to the prevention and treatment of this chronic condition. Identified by the leaders in the field as promising areas in diabetes research, the Focus provides a valuable resource for clinicians and researchers alike.