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Antiviral nanoparticle-formulated mimics of heparan sulfate proteoglycans were developed and shown to permit strong viral association as well as inhibition of a range of viruses on in vitro and in vivo models of infection.
Strategies to incorporate a lithium-cation source in lithium-ion capacitors have so far proved challenging. A sacrificial organic lithium salt is now shown to irreversibly provide lithium cations to a graphite electrode during the initial operando charging step without any negative effects.
Using a sol–gel process, monoliths of metal–organic frameworks were fabricated. With an enhanced methane volumetric uptake of 259 cm3 (STP) cm−3, and robust mechanical properties, this meets technological targets.
Isotope engineering in hexagonal boron nitride can affect its vibrational, electronic and optical properties due to the isotope substitution, as well as induce a change in the van der Waals interactions.
The Berezinskii–Kosterlitz–Thouless transition is observed in a 2D gas of exciton-polaritons, through measurements of the first-order coherence both in space and time.
Proceeding from quantum mechanical predictions, a high shear piezoelectric constant of 178 pm V−1 was measured for the amino acid crystal beta glycine. This originates from the efficient packing of the molecules of the amino acid.
Colloidal chiral springs and helices are formed by light inside a nematic liquid crystal suspension, predefining the mesoscopic superstructures self-assembled in such systems.
In situ transmission electron microscopy combined with theory modelling reveals that surface segregation in CuAu solid solution generates misfit dislocations, providing atomistic mechanisms of dislocation nucleation and dynamics at heterointerfaces.
Metallic stents have been widely used in coronary angioplasty. Here, the authors develop a resorbable self-expanding stent from polymeric elastomers with high mechanical strength for coronary applications.
The exchange bias effect in IrMn/FeCo is driven by a phase transition in the IrMn layer at room temperature, and occurs without the typical field-cooling sequence across the antiferromagnet Neel temperature.
An in-plane memory device based on multidomain BiFeO3 thin films is reported. Highly conductive domain walls appear only during the application of a read-out field, a non-destructive process that reduces accumulation of mobile defects on the walls.
Core/shell type-I semiconductor nanocrystals with compositionally graded shell and embedded in a current-focusing device architecture reach population inversion, a condition required for lasing, when excited with direct current.
Angiogenesis has been implicated in fibrotic diseases of the liver. Here, the authors developed microniches that mimic angiogenesis during different stages of liver fibrosis, and demonstrate the role of mechanotransduction in fibrogenesis.
The activation of cleavable organometallic dimers upon exposure to ultraviolet radiation allows air-stable n-type doping of organic materials with electron affinity lower than the expected thermodynamic reducing strength of the dimers.
An approach to form protein-based hydrogels in living cells that resemble physiological hydrogel-like size-dependent molecular sieves is presented. Synthetic RNA granules mimics are obtained by functionalizing these entities with RNA-binding motifs.
Integrins play an important role in the adhesion of cells to their matrix. Here, the authors investigate how fibroblasts respond to mechanical loads, at the onset of cell adhesion to fibronectin, in distinct phases that are modulated by integrins.
The physical properties of biomaterials affect cell behaviour. Here, the authors investigate how stiffness and degradation of hydrogels affect signalling pathways that modulate the maintenance of stemness of neural progenitor cells.