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The frontal pole cortex is thought to be the most complex of all frontal cortex areas. Overcoming technical obstacles to direct recordings, a study in this issue finds that neurons in this area have unexpectedly simple response properties.
A study in this issue presents a new mouse model that directly tests the glutamate hypothesis of schizophrenia. The study reports that a decrease in NMDA receptor signaling during a particular developmental window in interneurons can induce cellular and behavioral changes similar to those seen in schizophrenia.
A new study shows that the Na+/K+ ATPase can function as an integrator of spike activity and interacts with a K+ conductance to provide a cellular short-term memory of locomotion in the Drosophila larval motor circuit.
